绝经后代谢综合征女性患者血尿酸水平与骨密度的关系

发布时间：2018-06-13 08:32

  本文选题：绝经后 + 代谢综合征　； 参考：《广东医学》2017年23期

【摘要】：目的探讨绝经后代谢综合征(MS)女性患者正常范围内血尿酸水平与腰椎及股骨颈骨密度之间的关系。方法选取绝经后MS女性患者156例,其血尿酸水平均在正常范围(150.0~360.0μmol/L)内,以血尿酸均值(252.0μmol/L)为界分为A、B两组,A组患者尿酸水平≥150.0且≤252.0μmol/L,B组患者尿酸水平252.0且≤360.0μmol/L。比较两组患者的临床生化指标和骨密度的差异。分析尿酸水平与腰椎及股骨颈骨密度之间的关系。结果 (1)B组患者的体质指数、收缩压、高血压百分比明显高于A组,差异有统计学意义(P0.05);(2)B组患者的三酰甘油、肌酐、尿素氮、尿酸、腰椎骨密度明显高于A组,差异有统计学意义(P0.05);(3)患者的腰椎骨密度与尿酸呈正相关,有统计学意义(r=0.349,P=0.029),股骨颈骨密度与尿酸无相关关系,无统计学意义(r=0.186,P=0.258);(4)尿酸与骨质疏松诊断的ROC曲线提示尿酸对骨质疏松的诊断有意义(AUC=0.773,P=0.047)。结论在尿酸水平正常的绝经后MS妇女中,尿酸水平与腰椎骨密度呈正相关,而与股骨颈骨密度无相关关系。
[Abstract]:Objective to investigate the relationship between serum uric acid level and bone mineral density of lumbar vertebrae and femoral neck in postmenopausal metabolic syndrome (MS) women. Methods 156 postmenopausal MS women were selected. The serum uric acid levels were within the normal range of 150.0 渭 mol / L, and the mean value of uric acid was 252.0 渭 mol / L, which was divided into two groups: group A, with uric acid level 鈮，

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