超微血流成像技术评估类风湿关节炎患者手指关节亚临床炎

发布时间：2018-07-12 11:09

本文选题：关节炎 + 类风湿　；参考：《中国医学影像技术》2016年05期

【摘要】：目的探讨超微血流成像技术(SMI)评价类风湿关节炎(RA)患者手指关节亚临床活动性炎症反应的应用价值。方法对临床缓解的30例RA患者480个手指关节(双手2~5指掌指关节和近节指间关节)滑膜区进行SMI检查,半定量评分系统对滑膜区血流进行分级,并与能量多普勒(PDUS)对比分析,比较两种检查结果的一致性。结果临床缓解的30例患者中,PDUS和SMI显示的缓解率分别为56.67%(17/30)和26.67%(8/30),差异有统计学意义(P=0.035)。在480个受检关节中,PDUS对滑膜区血流信号的显示率为8.54%(41/480),SMI血流信号显示率为12.50%(60/480),差异有统计学意义(P0.001)。PDUS与SMI对滑膜血流分级结果有高度一致性(Kappa=0.732,P0.001)。结论 SMI技术可更敏感地显示临床缓解期RA患者手指关节滑膜区异常血流信号。
[Abstract]:Objective to evaluate the application value of ultramicro flow imaging (SMI) in evaluating the subclinical active inflammatory response of finger joints in patients with rheumatoid arthritis (RA). Methods a SMI examination was performed on the synovial region of the 480 finger joints (hands of the hands and the proximal interphalangeal joints) of 30 patients with RA and the blood flow in the synovial region by the semi quantitative scoring system. The results were compared with energy Doppler (PDUS), and the consistency of the results of the two tests was compared. Results in 30 patients with clinical remission, the remission rates of PDUS and SMI were 56.67% (17/30) and 26.67% (8/30) respectively, and the difference was statistically significant (P=0.035). In the 480 tested joints, the rate of display of the blood flow signal in the synovial region was 8.54%. (41/480) the blood flow signal of SMI was 12.50% (60/480), and the difference was statistically significant (P0.001).PDUS and SMI were highly consistent with the results of the synovial flow classification (Kappa=0.732, P0.001). Conclusion SMI technique can more sensitively show the abnormal blood flow signal of the synovial area of the finger joint in the clinical remission stage of the RA.
【作者单位】：北京大学人民医院超声科;
【分类号】：R593.22

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