糖尿病足严重程度评估指标的相关性分析

发布时间：2018-07-26 13:50

【摘要】：目的探讨糖尿病足Wagner分级相关的评估指标。方法选取2001年11月-2015年4月于解放军空军总医院收治的1 578例糖尿病足(DF)患者(排除1型、特殊类型DM足患者21例,Wagner 0级28例,以及数据缺失较大193例)临床资料,依据Wagner分级分为5组,对5组间资料进行方差分析、χ~2检验和Spearmen等级相关性分析。结果 1 578例DF患者中,Wagner 1~5级分别为73例(4.6%)、241例(15.3%)、280例(17.7%)、945例(59.9%)及39例(2.5%)。随着Wagner分级的增高,DF患者的C反应蛋白(CRP)、血沉(ESR)、铁蛋白、住院费用、糖化血红蛋白(Hb A1c)、空腹血糖(FBG)、住院时间偏高,糖尿病周围血管病变(PAD)、糖尿病周围神经病变(DPN)、糖尿病视网膜病变(DR)的发病率也偏高,而血红蛋白(Hb)及体重指数(BMI)偏低,差异有统计学意义(P0.05)。相关性分析显示,PAD、DPN、Hb A1c、FBG及感染指标(CRP、ESR、铁蛋白)与DF严重程度呈正相关(P0.05);而营养指标(Hb、BMI)与DF严重程度呈负相关(P0.05)。结论PAD、DPN、Hb A1c、FBG、感染以及全身营养状况与DF严重程度相关。
[Abstract]:Objective to evaluate the Wagner grading of diabetic foot. Methods from November 2001 to April 2015, 1 578 cases of diabetic foot (DF) (28 cases of type 1, 21 cases of special type DM foot with grade 0, and 193 cases of large data deficiency) were selected and treated in PLA Air Force General Hospital from November 2001 to April 2015. According to the Wagner grade, the data were divided into 5 groups. The data were analyzed by ANOVA, 蠂 ~ 2 test and Spearmen grade correlation analysis. Results among the 1 578 cases of DF, 73 cases (4.6%) were classified as Wagner grade 1, 241 cases (15.3%) were treated with FN, and 945 cases (59.9%) were diagnosed and 39 cases (2.5%) were diagnosed. C reactive protein (CRP), erythrocyte sedimentation rate (ESR), (ESR), ferritin, hospitalization cost, HbA1c, fasting blood glucose (FBG), hospitalization time were higher with the increase of Wagner grade in DF patients. The incidence of (PAD), diabetic peripheral neuropathy (DPN), diabetic retinopathy (DR) was also high while hemoglobin (Hb) and body mass index (BMI) were lower (P0.05). The correlation analysis showed that there was a positive correlation between the severity of DF and the severity of DF (P0.05), but a negative correlation between the severity of DF and the severity of DF (P0.05). Conclusion the severity of DF is related to the infection and nutritional status of PADN HbA1cFBG.Conclusion the severity of DF is related to the infection and the nutritional status of the whole body.
【作者单位】：解放军空军总医院内分泌科;北京市石景山医院内分泌科;北京市密云县医院内分泌科;
【分类号】：R587.2

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