甘油三酯与臂踝动脉脉搏波传导速度的关系

发布时间：2019-01-04 15:51

【摘要】：目的:探讨甘油三酯与臂踝动脉脉搏波传导速度(baPWV)的关系。方法:选择开滦研究人群(卒中队列5 219例、老年人群队列1 754例、妊娠高血压队列1 561例、外周血管疾病筛查人群14 088例)共22 622例完成baPWV检测,采用偏相关分析甘油三酯与baPWV的相关性,多因素线性回归、多因素Logistic回归分析甘油三酯对baPWV的影响。结果:在22 622例人群中,排除甘油三酯缺失909例,最终纳入研究队列的为21 713例。结果显示,随着甘油三酯水平的增加,平均baPWV水平和baPWV≥1400 cm/s的检出率均呈上升趋势,偏相关分析结果表明甘油三酯与baPWV之间呈正相关(r=0.235),校正年龄、性别后甘油三酯与baPWV仍呈正相关(r=0.080)。Logistics回归分析表明,校正其他混杂因素后甘油三酯第二分位组、第三分位组、第四分位组与甘油三酯第一分位组相比均是baPWV≥1 400 cm/s的危险因素,比值比及95%可信区间分别为1.161(1.035~1.302)、1.312(1.165~1.476)、1.652(1.463~1.865)。结论:甘油三酯与脉搏波传导速度呈正相关,甘油三酯与脉搏波传导速度独立关联。
[Abstract]:Objective: to investigate the relationship between triglyceride and brachial artery pulse wave velocity (baPWV). Methods: baPWV was detected in 22 622 patients (5 219 stroke cohort, 1 754 elderly population, 1 561 pregnancy hypertension cohort and 14 088 peripheral vascular disease screening population) in Kailuan study group. The correlation between triglyceride and baPWV, multivariate linear regression and multivariate Logistic regression analysis were used to analyze the effect of triglyceride on baPWV. Results: 909 cases of triglyceride deficiency were excluded from 22 622 subjects, and 21 713 cases were included in the study cohort. The results showed that the average baPWV level and the detection rate of baPWV 鈮，

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