老年男性代谢综合征与骨密度的相关性

发布时间：2019-01-05 04:06

【摘要】：目的探讨老年男性代谢综合征(MS)与骨密度(BMD)的关系。方法选取住院老年男性MS患者157例,根据是否合并骨质疏松(OP)分为两组,采用双能X线法检测BMD、计算体重指数(BMI),测量腰围(WC)、血压(BP),检测空腹血糖(FPG)、甘油三酯(TG)、总胆固醇(TC)、低密度脂蛋白胆固醇(LDL-C)、高密度脂蛋白胆固醇(HDL-C),分析老年男性MS的相关代谢因素与BMD的相关性。结果与非OP组(NOP)相比,OP组收缩压(SBP)、舒张压(DBP)、FPG、TG、TC、LDL-C水平明显增高(P0.05),BMI、WC、HDL-C水平明显降低(P0.05);Logistic回归分析显示OP组中BMD与BMI、WC呈正相关(r=0.235、0.182,P=0.000、0.011),与年龄、FPG、TG、LDL-C呈负相关(r=-0.325、-0.244、-0.090、-0.311,P=0.000、0.000、0.022、0.000),与TC无明显相关性(r=0.002,P=0.979)。结论老年男性代谢异常与BMD关系密切,在做好OP防治的同时,须重视代谢危险因素的干预。
[Abstract]:Objective to investigate the relationship between metabolic syndrome (MS) and bone mineral density (BMD) in elderly men. Methods 157 elderly male patients with MS were divided into two groups according to whether they were complicated with osteoporosis (OP). The body mass index (BMI),) of (WC), was measured by dual-energy X-ray method. (WC), blood pressure (BP), was measured by (BMI),. Fasting blood glucose (FPG), triglyceride (TG), total cholesterol (TG), low density lipoprotein cholesterol (LDL-C) and high density lipoprotein cholesterol (HDL-C) were measured. The correlation between MS metabolic factors and BMD was analyzed. Results compared with the control group, the systolic blood pressure (SBP),) diastolic blood pressure (SBP),) (DBP), FPG,TG,TC,LDL-C level in the OP group was significantly higher than that in the non OP group (P0.05), and the BMI,WC,HDL-C level was significantly decreased (P0.05). Logistic regression analysis showed that there was a positive correlation between BMD and BMI,WC in OP group (r = 0.235) and a negative correlation between BMD and age (r = 0.325- 0.244n- 0.090 / 0.311), and a negative correlation between BMD and age (r = 0.325- 0.244n- 0.090 / 0.311). There was no significant correlation with TC (P < 0. 0002, P < 0. 979). Conclusion there is a close relationship between metabolic abnormality and BMD in aged men. The intervention of metabolic risk factors should be paid more attention to in the prevention and treatment of OP.
【作者单位】：江西省人民医院老年科;
【分类号】：R589

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