合肥市40岁以上社区人群代谢综合征的患病现状及危险因素分析

发布时间：2019-03-05 11:33

【摘要】：目的了解合肥市社区人群代谢综合征(MS)的患病现状及其相关危险因素。方法针对中国糖尿病与肿瘤发生风险的前瞻性随访研究的基线调查资料,排除部分数据缺失、误差,选取有年龄、性别、既往史、身高、体重、腰臀围、血糖、血脂、血压等具有完整资料的40岁以上人群共9 977例进行分析。代谢综合征诊断标准采用2007年《中国成人血脂异常防治指南》修订定义。将调查对象分为正常组和MS组,采用t检验和χ2检验比较两组之间年龄、性别、血脂、体质指数(BMI)等指标的差异,采用Logistic回归分析MS发病的相关危险因素。结果合肥市40岁以上社区居民MS的粗患病率为27.6%,标化患病率为26.6%。MS患病率随着年龄增加逐渐增高,MS组患者血压、腰臀比、BMI、糖化血红蛋白等指标均较正常人群增高,差异均有统计学意义(P0.05)。多因素回归分析结果显示年龄、BMI、三酰甘油是MS的独立危险因素,而高密度脂蛋白胆固醇是代谢综合征的保护性因素。结论 MS发病率较高,与多种因素有关,应针对相关危险因素积极采取干预措施,预防疾病发生。
[Abstract]:Objective to investigate the prevalence and risk factors of metabolic syndrome (MS) in community population in Hefei. Methods the baseline data of prospective follow-up study of diabetes mellitus and tumor risk in China were investigated. Some data were excluded, including age, sex, previous history, height, weight, waist and hip circumference, blood sugar, blood lipid, and so on. A total of 9 977 people over 40 years old with complete data such as blood pressure were analyzed. The diagnostic criteria for metabolic syndrome were revised according to the 2007 guidelines for Prevention and treatment of dyslipidemia in Chinese Adults. The subjects were divided into normal group and MS group. T test and 蠂 2 test were used to compare the difference of age, sex, blood lipid and body mass index (BMI) between the two groups. Logistic regression was used to analyze the risk factors of MS. Results the crude prevalence of MS was 27.6% in community residents over 40 years old in Hefei. The standardized prevalence rate of 26.6%.MS increased with age. The blood pressure, waist hip ratio and BMI, in MS group were higher than those in control group. Glycosylated hemoglobin and other indicators were higher than the normal population, the difference was statistically significant (P0.05). Multivariate regression analysis showed that age was an independent risk factor for MS and high density lipoprotein cholesterol (HDL-C) was a protective factor for metabolic syndrome. BMI, triacylglycerol was an independent risk factor for MS. Conclusion the incidence of MS is high, which is related to many factors. We should take active intervention measures to prevent the occurrence of the disease according to the related risk factors.
【作者单位】：安徽医科大学合肥第三临床学院;合肥市第三人民医院内分泌科;合肥市第三人民医院海恒社区卫生服务中心;合肥市第三人民医院检验科;安徽医科大学第一附属医院内分泌科、安徽省内分泌与代谢病省级实验室;
【基金】：合肥市科技局重大科技项目(编号:2011043) 公益性行业科研专项经费(编号:201502007)
【分类号】：R589

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