B型尿钠肽测定在糖尿病性心肌病早期诊断的价值

发布时间：2019-07-28 19:18

【摘要】：目的探讨血浆B型尿钠肽(BNP)在糖尿病性心肌病患者中的诊断价值。方法选择高州市人民医院2010年7月至2013年7月门诊及住院的2型糖尿病性心肌病患32例为糖尿病性心肌病组;32例单纯2型糖尿病患者为单纯糖尿病组及32例健康人为健康对照组,采用免疫发光分析法测定3组的血浆BNP水平。结果对比糖化血红蛋白、胆固醇、三酰甘油和低密度脂蛋白胆固醇(LDL-C)的水平,糖尿病性心肌病组及单纯糖尿病组较健康对照组升高(P0.05);糖尿病性心肌病组的空腹血糖(FPG)以及BNP水平均与健康对照组相比明显升高,差异有统计学意义(P0.01);糖尿病心肌病组FPG、LDL-C以及BNP水平均高于单纯糖尿病组,差异有统计学意义(P0.05)。结论测定BNP水平可作为预测糖尿病性心肌病早期诊断和筛查指标之一。
[Abstract]:Objective to evaluate the diagnostic value of plasma B-type natriuretic peptide (BNP) in patients with diabetic cardiomyopathy. Methods from July 2010 to July 2013, 32 patients with type 2 diabetic cardiomyopathy, 32 patients with simple type 2 diabetes mellitus and 32 healthy controls were selected from Gaozhou people's Hospital. Plasma BNP levels were measured by immunoluminescence assay. Results the levels of glycosylated hemoglobin, cholesterol, triacylglycerol and low density lipoprotein cholesterol (LDL-C) in diabetic cardiomyopathy group and diabetic cardiomyopathy group were significantly higher than those in healthy control group (P 0.05), and the fasting blood glucose (FPG) and BNP levels in diabetic cardiomyopathy group were significantly higher than those in healthy control group (P 0.01). The levels of FPG,LDL-C and BNP in diabetic cardiomyopathy group were significantly higher than those in diabetic cardiomyopathy group (P 0.05). Conclusion the determination of BNP level can be used as one of the predictors of early diagnosis and screening of diabetic cardiomyopathy.
【作者单位】：广东省高州市人民医院检验科;
【分类号】：R587.2

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