盐酸左西替利嗪片联合白芍总苷胶囊治疗皮炎湿疹的临床疗效

发布时间：2018-02-28 23:34

本文关键词： 湿疹盐酸左西替利嗪片白芍总苷胶囊　出处：《中华中医药学刊》2017年11期 　论文类型：期刊论文

【摘要】：目的:探讨盐酸左西替利嗪片联合白芍总苷胶囊治疗皮炎湿疹的临床效果。方法:选取皮炎湿疹患者300例,采用随机数表法将所有的患者分为观察组和对照组,每组各150例。对照组患者给予盐酸左西替利嗪片治疗,观察组在对照组患者的基础上联合白芍总苷胶囊治疗,比较两组患者治疗后不良反应发生率、临床效果以及外周血Th1/Th2变化情况。结果:治疗前,两组患者的外周血Th1/Th2进行比较无显著差异(P0.05);治疗后,两组患者的外周血Th1/Th2都有所上升,观察组(7.45±1.39)%高于对照组(5.88±1.56)%,两组患者进行比较,差异显著(P0.05);观察组患者治疗后的总有效率为96.00%,对照组患者治疗后的总有效率为80.00%,观察组高于对照组,两组比较差异显著(P0.05);两组患者的治疗后不良反应发生率进行比较,无显著差异(P0.05)。结论:盐酸左西替利嗪片联合白芍总苷胶囊治疗皮炎湿疹患者效果显著,且不良反应发生率低,安全性高。
[Abstract]:Objective: to investigate the clinical effect of levatirizine hydrochloride combined with total glucoside capsule of paeony on dermatitis eczema. Methods: 300 patients with dermatitis and eczema were randomly divided into observation group and control group. There were 150 cases in each group. The patients in the control group were treated with levcetirizine hydrochloride tablets, and the patients in the observation group were treated with total paeony glucoside capsule on the basis of the control group. The incidence of adverse reactions after treatment was compared between the two groups. Results: before treatment, there was no significant difference in peripheral blood Th1/Th2 between the two groups. The observation group (7.45 卤1.39)% was higher than the control group (5.88 卤1.56), the difference between the two groups was significant (P 0.05), the total effective rate of the observation group after treatment was 96.00%, the total effective rate of the control group was 80.00g, the observation group was higher than the control group. There was no significant difference in the incidence of adverse reactions between the two groups (P 0.05). Conclusion: the efficacy of levcetirizine hydrochloride combined with total glucoside of paeony in treating dermatitis and eczema is significant, and the incidence of adverse reactions is low. High safety.
【作者单位】：河北省中医药科学院皮肤科;
【基金】：河北省科技计划项目(12276104D-56)
【分类号】：R758.23

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