中药痒疹方联合卡泊三醇软膏及卤米松乳膏治疗结节性痒疹29例临床观察

发布时间：2018-04-18 01:21

本文选题：痒疹 + 结节性　；参考：《中国皮肤性病学杂志》2015年02期

【摘要】：目的观察中药痒疹方联合卡泊三醇软膏和卤米松乳膏治疗结节性痒疹的临床疗效和安全性。方法将入选的87例结节性痒疹患者随机分为3组,各29例。全部患者日煎1剂中药痒疹方(组分:生地、土茯苓和蒺藜各30g,金银藤15g,荆芥、防风、红花、赤芍、三棱和莪术各10g)分早、晚服用。另外,治疗组每日早、晚各1次外搽卡泊三醇软膏,对照组每日早、晚各1次外搽卤米松乳膏,联合治疗组每日晨外搽卡泊三醇软膏1次,晚间外搽卤米松乳膏0.5h后再外用卡泊三醇软膏1次。治疗4周后判定疗效,治疗结束后随访2个月。结果治疗4周后,3组患者的结节数目、瘙痒程度和皮损积分均优于其治疗前,且联合治疗组均低于对照组和治疗组,联合治疗组有效率(75.86%)高于对照组(62.07%)和治疗组(51.72%),差异均有统计学意义(P均0.05)。三组患者均无不良反应。结论中药痒疹方联合卡泊三醇软膏和卤米松乳膏治疗结节性痒疹疗效显著,无不良反应。
[Abstract]:Objective to observe the clinical efficacy and safety of prurigo decoction combined with carpotriol ointment and halomethasone cream in the treatment of prurigo nodosum.Methods 87 patients with prurigo nodule were randomly divided into 3 groups, 29 cases each.All patients were treated with 1 dose of prurigo recipe (30 g each, 30 g each, 15 g of honeysuckle, 10 g of red peony, 10 g of red peony, 10 g of red peony, 10 g of red peony, 10 g of red peony, 10 g of red peony, 10 g of red peony and 10 g of zedoary curcuma).In addition, the treatment group was treated with carpotriol ointment once a day, the control group was treated with halomethasone cream once a day, the control group was treated with carpotriol ointment once a day, and the control group was treated with carpotriol ointment once a day.Apply halomisone cream 0.5 h later, then use carpotriol ointment once.The curative effect was evaluated after 4 weeks and followed up for 2 months after treatment.Results after 4 weeks of treatment, the number of nodules, the degree of pruritus and the score of skin lesion in the three groups were better than those before treatment, and those in the combined treatment group were lower than those in the control group and the treatment group.The effective rate of the combined treatment group (75.86) was higher than that of the control group (62.07%) and the treatment group (51.722%). The difference was statistically significant (P < 0.05).There were no adverse reactions in all three groups.Conclusion the curative effect of prurigo decoction combined with carpotriol ointment and halomethasone cream on prurigo nodosum is remarkable and there is no adverse reaction.
【作者单位】：天津中医药大学;天津市中西医结合医院皮肤科;
【分类号】：R758.31

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