依巴斯汀联合白芍总苷治疗人工荨麻疹血虚风燥证临床疗效客观评价

发布时间：2018-05-10 15:50

本文选题：人工荨麻疹 + 白芍总苷　；参考：《南京中医药大学》2012年硕士论文

【摘要】：目的：人工荨麻疹是一种常见病、多发病,导师运用依巴斯汀(开思亭)加白芍总苷治疗人工荨麻疹血虚风燥证收到了较好的疗效,本课题旨在探讨该方的临床疗效及其复发情况,从而为此方在临床广泛运用提供理论支持并为进一步研究做准备。方法：将90例血虚风燥型人工荨麻疹患者分成三组。治疗组30例患者给予白芍总苷合依巴斯汀治疗；对照1组30例,给予单纯依巴斯汀治疗；对照2组30例自拟方加减联合依巴斯汀治疗。分别观察三组疗效,观察时间为4周。观察三组治疗前后瘙痒、风团数目、风团大小、风团发作频率、风团持续时间等总积分和其疗效指数以及不良反应、复发等情况。结合医生评分和病人自我总评价两方面得出结论。结果：三组患者的年龄、病程相比较,均无显著性差异,具有可比性。治疗组总显效率为90.00%,对照l组总显效率为50.00%,对照2组总显效率为86.67%。三组治疗1个月临床疗效比较,治疗组和对照1组治疗后各症状总积分较治疗前均有下降,具有显著性差异(P0.05)；治疗组和对照2组治疗后各症状积分较治疗前均有下降,不具有显著性差异(P0.05)；治疗组和对照2组均优于对照1组,差异具有统计学意义(P0.05)。结论：白芍总苷联合依巴斯汀治疗人工荨麻疹血虚风燥证是有效的方法,其近期疗效基本等同于依巴斯汀联合自拟方,并有较好的防止和控制复发的效果。
[Abstract]:Objective: artificial urticaria is a kind of common disease, frequent incidence, the teacher used Ebastine (Cassitin) plus total paeony glucoside treatment artificial urticaria blood deficiency wind dryness syndrome received better curative effect. The purpose of this study is to investigate the clinical efficacy and recurrence of the prescription, so as to provide theoretical support and prepare for further study. Methods: 90 cases of artificial urticaria with blood deficiency and wind dryness were divided into three groups. 30 patients in the treatment group were treated with total glucoside of paeony combined with epastatin, 30 patients in the control group were treated with Evastin alone, and 30 patients in the control group were treated with self-made prescription plus or subtraction combined with Evastin. The curative effect of the three groups was observed for 4 weeks. The total scores of pruritus, wind mass number, wind mass size, wind mass attack frequency, wind mass duration, curative effect index, adverse reaction and recurrence were observed before and after treatment in the three groups. Combined with doctor's score and patient's self-evaluation, the conclusion was drawn. Results: there was no significant difference in age and course of disease among the three groups. The total effective rate of treatment group was 90.00g, that of control group l was 50.00g, that of control group 2 was 86.67. The total scores of symptoms in the treatment group and the control group were all decreased after treatment, with significant difference (P 0.05), and the scores of each symptom in the treatment group and the control group were lower than those before treatment, and the scores of each symptom in the treatment group and the control group after treatment were lower than those before treatment, and there was a significant difference between the treatment group and the control group after treatment (P < 0.05). There was no significant difference between treatment group and control group (P 0.05), but the difference between treatment group and control group was better than that of control group 1 (P 0.05). Conclusion: total glucoside of paeony combined with Ebastine is an effective method for the treatment of artificial urticaria with blood deficiency and wind dryness, and its short-term curative effect is basically the same as that of Ebastine combined with self-prescription, and it has a better effect of preventing and controlling recurrence.
【学位授予单位】：南京中医药大学
【学位级别】：硕士
【学位授予年份】：2012
【分类号】：R758.24

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