大连地区926例化妆品皮肤病临床分析

发布时间：2018-05-30 16:46

本文选题：化妆品 + 皮肤病　；参考：《大连医科大学》2011年硕士论文

【摘要】：目的:总结、分析化妆品皮肤病的临床特点和引起化妆品皮肤病的化妆品类型。方法:对926例化妆品皮肤病进行了临床分析,对患者进行可疑化妆品斑贴试验。结果:化妆品皮肤病临床表现主要为接触性皮炎(90.28%),其次是色素沉着(3.78%)、痤疮样损害(3.24% )、光感性皮炎(2.16%)、接触性荨麻疹(0.54%)。可疑致病化妆品种类2019种,以护肤品为主(92%),926例患者中斑贴试验阳性者359例,阳性率38.77%。结论:化妆品皮肤病的发生原因是多方面的:(1)化妆品的普遍使用;(2)化妆品质量低劣、微生物污染、有毒物质含量超标、化工原料的毒性刺激、违规添加药品、产品说明书交待不清;(3)对化妆品的类型选择和使用不当,出现不适时未及时停用化妆品并到正规医院就诊。所以对化妆品不良反应的防治和化妆品的卫生管理应注重致敏物质的监测,为了进一步探讨引起不良反应的化妆品成分,建议做仿欧标准抗原的斑试。预防化妆品皮肤病,需要与化妆品有关的企业、研究院所、销售和消费者以及皮肤科医生的共同努力。加强对消费者进行有关化妆品皮肤病知识的宣传,建立一个完整的化妆品皮肤病监测系统。
[Abstract]:Objective: to summarize and analyze the clinical characteristics of cosmetic dermatosis and the types of cosmetics. Methods: 926 cases of cosmetic dermatosis were analyzed. Results: the main clinical manifestations of cosmetic dermatosis were contact dermatitis 90.28m, pigmentation 3.78%, acne lesion 3.24%, photogenic dermatitis 2.16%, contact urticaria 0.54g. There were 2019 kinds of suspected pathogenic cosmetics, of which 359 cases were positive in patch test, and the positive rate was 38.77% in 926 cases of skin care products. Conclusion: the cause of cosmetic dermatosis is the common use of cosmetics in many aspects, such as poor quality, microbial pollution, excessive toxic substance content, toxic stimulation of chemical raw materials, illegal addition of drugs, etc. The product description is not clear about the choice and use of cosmetics, and it is not timely to stop cosmetics and go to the regular hospital. Therefore, the prevention and treatment of adverse reactions of cosmetics and hygiene management of cosmetics should pay attention to the monitoring of sensitizing substances. In order to further explore the components of cosmetics causing adverse reactions, it is suggested to do spot tests imitating European standard antigens. The prevention of cosmetic dermatosis requires the joint efforts of cosmetic companies, research institutes, sales and consumers, and dermatologists. Strengthen the promotion of cosmetics dermatology knowledge to consumers, and establish a complete cosmetic dermatology monitoring system.
【学位授予单位】：大连医科大学
【学位级别】：硕士
【学位授予年份】：2011
【分类号】：R758.2

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