神经梅毒18例临床分析

发布时间：2018-06-19 04:36

  本文选题：神经梅毒 + 脑脊液　； 参考：《中国老年保健医学》2015年05期

【摘要】：目的探讨神经梅毒的临床表现、实验室检查和影像学检查特征。方法回顾性分析18例神经梅毒患者的临床表现、实验室检查和影像学检查资料。结果 18例神经梅毒患者平均发病年龄53.83岁,其中主质型8例(44.44%),其中麻痹性痴呆4例,脊髓痨3例,混合型1例;脑膜血管梅毒4例(22.22%);无症状型3例(16.67%);树胶样肿型2例(11.11%);脑膜炎型1例(5.56%)。血清血浆快速反应素试验(RPR)、梅毒螺旋体颗粒凝集试验(TPPA)检测均为阳性。脑脊液检查:18例患者TPPA均阳性,9例RPR阳性,9例脑脊液白细胞数≥10×106/L,7例脑脊液蛋白0.50g/L。影像学表现为:脑梗死,脑萎缩,脑白质变性,额叶、颞叶、海马区异常信号及大脑后动脉闭塞,颅内动脉硬化。结论神经梅毒表现多样,临床体征、血清学、脑脊液及影像学对于诊断神经梅毒及分型有重要指导意义。
[Abstract]:Objective to investigate the clinical manifestations, laboratory and imaging features of neurosyphilis. Methods 18 cases of neurosyphilis were analyzed retrospectively. Results the average age of 18 patients with neurosyphilis was 53.83 years old. Among them, 8 cases had primary type of neurosyphilis (4 cases of paralytic dementia, 3 cases of tuberculosis and 1 case of mixed type). Meningeal vascular syphilis (n = 4), asymptomatic type (n = 3, n = 16), gum type (n = 2, n = 11) and meningitis type (n = 1, n = 5.56). Serum rapid response hormone test (RPRP) and Treponema pallidum agglutination test (TPPA) were all positive. Cerebrospinal fluid (CSF) examination showed TPPA positive in 9 cases and RPR positive in 9 cases. WBC count in cerebrospinal fluid was 鈮，

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