激光治疗皮肤血管性疾病的临床分析

发布时间：2018-06-20 21:24

本文选题：皮肤血管性疾病 + 治疗方法　；参考：《浙江大学》2010年硕士论文

【摘要】： 研究目的：观察595nm波长可调脉宽的脉冲染料激光治疗各类型皮肤血管性疾病的临床疗效和不良反应。研究方法：收集我院皮肤科激光门诊2008年10月到2009年3月间的105例选择性皮肤血管性疾病病例。回顾性实境研究皮肤血管性疾病管理数据库中年龄、皮损类型、部位、激光治疗前后的疗效及副作用。并随访超过2个月,了解其不适症状是否较前改善。研究结果： 595nm波长可调脉宽的脉冲染料激光治疗皮肤血管性疾病的总有效率分别为：鲜红斑痣79.45%,草莓状血管瘤96.00%,混合性血管瘤25.00%,而海绵状血管瘤基本无效。年龄越小,疗效越好(P0.01～0.05)；眼周、头面部及颈部皮损疗效较好(P0.01～0.05)。术后副作用以充血水肿发生率较高,几乎所有患者治疗后均有不同程度的暂时性充血水肿,约4-5天即可消退,出现萎缩性疤痕患者2例(1.90%)。结论： 595nm波长可调脉宽的脉冲染料激光是治疗血管性皮肤病的第三代染料激光,具有穿透较深的波长和脉宽1.5-40ms的长脉宽,几乎适用于各种管径的病变血管,治疗后不良反应轻微,仅有少部分患者遗留疤痕及色素减退等副作用。595nm波长可调脉宽的脉冲染料激光治疗皮肤血管异常性疾病安全性高,疗效确切,是目前较理想的治疗方法。
[Abstract]:Objective: to observe the clinical efficacy and adverse reactions of 595nm wavelength adjustable pulse width pulsed dye laser in the treatment of various types of cutaneous vascular diseases. Methods: 105 cases of selective cutaneous vascular diseases were collected from October 2008 to March 2009. A retrospective study of age, lesion type, site, efficacy and side effects before and after laser therapy in the skin vascular disease management database was conducted. The patients were followed up for more than 2 months to see if the symptoms were improved. Results: the total effective rates of pulsed dye laser with 595nm wavelength adjustable pulse width in treating skin vascular diseases were 79.45, 96.00, 25.00 and 25.00 respectively, while cavernous hemangioma was ineffective. The younger the age, the better the curative effect was, and the better the curative effect was around the eye, head, face and neck. The incidence of postoperative side effects was high, almost all patients had temporary hyperemia edema in varying degrees after treatment, which could be receded in about 4-5 days, and 2 patients with atrophic scar were found to have atrophic scar (1.90%). Conclusion: the pulse dye laser with adjustable pulse width of 595nm wavelength is the third generation dye laser for the treatment of vascular dermatosis. It has the characteristics of penetrating deeper wavelength and long pulse width of 1.5-40ms. The adverse reaction after treatment was mild, and only a few patients had some side effects, such as scar and hypopigmentation. The pulse dye laser with adjustable pulse width at 595 nm was safe and effective in the treatment of skin vascular abnormalities. It was an ideal treatment method at present.
【学位授予单位】：浙江大学
【学位级别】：硕士
【学位授予年份】：2010
【分类号】：R758.6

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