刮痧联合氯雷他定治疗慢性荨麻疹的临床研究

发布时间：2019-03-01 07:21

【摘要】：目的：通过对刮痧联合氯雷他定治疗慢性荨麻疹患者疗效的随机对照临床观察研究,探讨其治疗机理,以选出一种安全有效、简便价廉的治疗方法,进一步提高中西医结合治疗该病的有效率。方法：将166例慢性荨麻疹患者随机分为三组,治疗组采取阶段式逐步减量的方法予氯雷他定口服联合每周1次刮痧治疗；氯雷他定对照组采取阶段式逐步减量的方法予氯雷他定口服；刮痧对照组予刮痧治疗每周1次。对三组患者连续治疗12周,观察其症状体征及不良反应,并对风团状况和瘙痒程度进行评分和疗效评定。结果：本研究结果表明：(1)治疗6周后疗效比较：治疗组56例,痊愈7例,显效20例,有效21例,无效8例,有效率85.71%；氯雷他定组58例,痊愈6例,显效17例,有效20例,无效15例,有效率74.14%；刮痧组52例,痊愈0例,显效13例,有效20例,无效19例,有效率63.46%。(2)治疗12周后疗效比较：治疗组56例,痊愈16例,显效18例,有效15例,无效7例,有效率87.50%：氯雷他定组58例,痊愈13例,显效18例,有效16例,无效11例,有效率81.03%；刮痧组52例,痊愈1例,显效11例,有效18例,无效22例,有效率57.69%。结论：治疗组疗效优于氯雷他定组和刮痧组,未见严重不良反应。刮痧联合氯雷他定治疗慢性荨麻疹安全、可靠、简便,能有效改善皮肤症状,尤其在迅速缓解瘙痒症状方面有优势。
[Abstract]:Objective: to explore the therapeutic mechanism of scraping combined with loratadine in the treatment of chronic urticaria by randomized controlled clinical study, so as to select a safe, effective, simple and inexpensive treatment method. Further improve the effective rate of integrated traditional Chinese and western medicine in the treatment of the disease. Methods: 166 patients with chronic urticaria were randomly divided into three groups. The treatment group was treated with oral loratadine combined with scrapping once a week. Loratadine control group was given loratadine orally by step-by-step reduction and scraping control group was given scraping treatment once a week. Three groups of patients were treated for 12 weeks, the symptoms, signs and adverse reactions were observed, and the condition of wind mass and the degree of itching were evaluated and the curative effect was evaluated. Results: (1) after 6 weeks of treatment, 56 cases were cured, 7 cases were cured, 20 cases were markedly effective, 21 cases were effective, 8 cases were ineffective, and the effective rate was 85.71%. Of 58 cases in loratadine group, 6 cases were cured, 17 cases were markedly effective, 20 cases were effective and 15 cases were ineffective. The effective rate was 74.14%. (2) after 12 weeks of treatment, 56 cases in the treatment group were cured, 16 cases were cured, 18 cases were markedly effective, 15 cases were effective, 7 cases were ineffective, and the effective rate was 63.46%. The effective rate was 87.50%: in the loratadine group, 58 cases were cured, 13 cases were cured, 18 cases were obviously effective, 16 cases were effective, 11 cases were ineffective, and the effective rate was 81.03%. In the scraping group, 52 cases were cured, 11 cases were markedly effective, 18 cases were effective, 22 cases were ineffective, and the effective rate was 57.69%. Conclusion: the therapeutic effect in the treatment group is better than that in the loratadine group and the scraping group, and there is no serious adverse reaction. Scraping combined with loratadine in the treatment of chronic urticaria is safe, reliable, simple and can effectively improve skin symptoms, especially in the rapid relief of itching symptoms.
【学位授予单位】：成都中医药大学
【学位级别】：硕士
【学位授予年份】：2011
【分类号】：R758.24

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