22MHz高频超声在健康人群中皮肤生理及声像研究
发布时间：2019-05-24 22:30
【摘要】：研究背景皮肤是人体抵御外界环境损害的第一道屏障。通过对中国健康人群的皮肤生理指标检测,可以提高皮肤科临床医生对皮肤疾病的认识、诊断和疗效评价。传统超声成像体系由于分辨率不够,深度不够浅表和探头过大(超声换能器)而不适用于皮肤病学。随着高频超声皮肤影像仪的发展,高频超声成像目前已经应用于皮肤病学领域。因为高频超声皮肤影像仪具有的高频率和高分辨率特性,它不仅可以清晰的显示皮肤各层结构,而且可以精确的侧量皮肤厚度与皮肤回声密度。皮肤科医生在高频超声成像系统的帮助下,可以诊断出皮肤病的众多适应症。皮肤厚度和皮肤回声密度是皮肤生理一般监测指标,一些常见的皮肤疾病如寻常型银屑病、关节型银屑病、特应性皮炎和硬皮病等发病过程都伴随着皮肤厚度和皮肤回声密度的变化。本研究主要检测中国健康人群的皮肤厚度、皮肤回声密度和皮肤声像图,探讨它们在不同性别、年龄和解剖部位差异性,以期为皮肤科医生在皮肤疾病诊断和疗效评价提供依据。目的用无创高频超声自动测量中国健康人群各年龄组皮肤厚度、皮肤回声密度及皮肤声像图研究,并检验它们在健康人群中是否存在统计学意义。方法应用22MHz高频超声分别对830名健康人群前额、面颊、前臂、手背、手掌、腹部、小腿、脚背8个不同解剖部位进行自动测量皮肤厚度、皮肤回声密度及皮肤声像图观察,并详细记录各组数据。结果22MHz高频超声可以清晰地显示皮肤各层结构,表皮层为一线状高回声;真皮层为中等回声,真皮下层可见管状低回声的皮下静脉;皮下脂肪层为低回声;浅筋膜为规则纵向走行的线状高回声。8个不同部位皮肤厚度中男性手掌皮肤最厚;女性脚背皮肤最薄。部位不同、性别不同均影响皮肤厚度且均具有统计学意义(p㩳0.05)。8个不同部位皮肤回声密度中女性小腿皮肤回声密度最高;男性前额皮肤回声密度最低。除面颊与手掌、前臂与手背、小腿与脚背,其它部位两两之间皮肤回声密度差异比较具有统计学意义(p㩳0.05)。除脚背部,其它部位性别不同其皮肤回声密度差异具有统计学意义(p㩳0.05)。结论22MHz高频超声可以清晰地显示皮肤各层结构及精确地测量皮肤厚度和皮肤回声密度。由于高频超声无创性,在皮肤病诊断、疗效评价、正常皮肤测量及监控、皮肤肿瘤和医疗美容中均扮演着重要的角色。
[Abstract]:Background skin is the first barrier against external environmental damage. Through the detection of skin physiological indexes of healthy people in China, the understanding, diagnosis and curative effect evaluation of skin diseases can be improved. The traditional ultrasonic imaging system is not suitable for dermatology because of its insufficient resolution, shallow depth and too large probe (ultrasonic transducer). With the development of high frequency ultrasound skin imager, high frequency ultrasound imaging has been used in dermatology. Because of the high frequency and high resolution characteristics of high frequency ultrasonic skin imager, it can not only clearly display the structure of each layer of the skin, but also accurately measure the thickness of the skin and the echo density of the skin. Dermatologists can diagnose many indications of dermatosis with the help of high frequency ultrasound imaging system. Skin thickness and skin echo density are general monitoring indexes of skin physiology. Some common skin diseases such as psoriasis vulgaris, psoriasis vulgaris, The pathogenesis of atopic dermatitis and scleroderma is accompanied by the change of skin thickness and skin echo density. The purpose of this study was to detect the skin thickness, skin echo density and skin sonography of healthy Chinese population, and to explore the differences of skin thickness, skin echo density and skin sonography in different genders, ages and anatomical sites. In order to provide the basis for dermatologists in the diagnosis and curative effect evaluation of skin diseases. Objective to automatically measure skin thickness, skin echo density and skin sonography in Chinese healthy population by noninvasive high frequency ultrasound, and to test whether there is statistical significance in healthy population. Methods the skin thickness, skin echo density and skin sonography of 830 healthy people were automatically measured by 22MHz high frequency ultrasound in 8 different anatomical parts of forehead, cheek, forearm, back of hand, palm, abdomen, calf and foot. The data of each group were recorded in detail. Results 22MHz high frequency ultrasound could clearly show the structure of each layer of the skin, the epidermis was linear hyperecho, the dermis was medium echo, the subcutaneous hypoechoic vein could be seen in the subdermis, and the subcutaneous fat layer was hypoechoic. The superficial fascia is a linear hyperecho with regular longitudinal direction. Among the 8 different skin thickness, the skin of the palm of the man is the thickest, and the skin of the back of the foot is the thinnest. The skin thickness was affected by different sites and gender (p 鈮，
本文编号：2485240
[Abstract]:Background skin is the first barrier against external environmental damage. Through the detection of skin physiological indexes of healthy people in China, the understanding, diagnosis and curative effect evaluation of skin diseases can be improved. The traditional ultrasonic imaging system is not suitable for dermatology because of its insufficient resolution, shallow depth and too large probe (ultrasonic transducer). With the development of high frequency ultrasound skin imager, high frequency ultrasound imaging has been used in dermatology. Because of the high frequency and high resolution characteristics of high frequency ultrasonic skin imager, it can not only clearly display the structure of each layer of the skin, but also accurately measure the thickness of the skin and the echo density of the skin. Dermatologists can diagnose many indications of dermatosis with the help of high frequency ultrasound imaging system. Skin thickness and skin echo density are general monitoring indexes of skin physiology. Some common skin diseases such as psoriasis vulgaris, psoriasis vulgaris, The pathogenesis of atopic dermatitis and scleroderma is accompanied by the change of skin thickness and skin echo density. The purpose of this study was to detect the skin thickness, skin echo density and skin sonography of healthy Chinese population, and to explore the differences of skin thickness, skin echo density and skin sonography in different genders, ages and anatomical sites. In order to provide the basis for dermatologists in the diagnosis and curative effect evaluation of skin diseases. Objective to automatically measure skin thickness, skin echo density and skin sonography in Chinese healthy population by noninvasive high frequency ultrasound, and to test whether there is statistical significance in healthy population. Methods the skin thickness, skin echo density and skin sonography of 830 healthy people were automatically measured by 22MHz high frequency ultrasound in 8 different anatomical parts of forehead, cheek, forearm, back of hand, palm, abdomen, calf and foot. The data of each group were recorded in detail. Results 22MHz high frequency ultrasound could clearly show the structure of each layer of the skin, the epidermis was linear hyperecho, the dermis was medium echo, the subcutaneous hypoechoic vein could be seen in the subdermis, and the subcutaneous fat layer was hypoechoic. The superficial fascia is a linear hyperecho with regular longitudinal direction. Among the 8 different skin thickness, the skin of the palm of the man is the thickest, and the skin of the back of the foot is the thinnest. The skin thickness was affected by different sites and gender (p 鈮，
本文编号：2485240
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