新发脑梗死后患者抑郁与认知损害程度的关系研究

发布时间：2018-01-30 03:04

本文关键词： 脑梗死抑郁认知障碍　出处：《中国全科医学》2017年S1期 　论文类型：期刊论文

【摘要】：目的探讨新发脑梗死后患者抑郁状况与认知损害程度的关系。方法选取2015年2月—2017年1月在厦门大学附属第一医院杏林分院神经内科就诊的83例新发脑梗死患者,持续4周进行汉密尔顿抑郁量表(HAMD)、抑郁自评量表(SDS)、简易智能精神状态检查量表(MMSE)、老年抑郁量表(GDS)监测评估,根据HAMD评分将患者分为抑郁组和非抑郁组;根据蒙特利尔认知评估量表(Mo CA)评分将患者分为无认知损害组、轻度认知损害组和严重认知损害组。结果严重认知损害组Mo CA、HAMD、MMSE、GDS评分均高于轻度认知损害组和无认知损害组,差异有统计学意义(P0.05)。抑郁组MMSE、SDS评分高于非抑郁组,差异有统计学意义(P0.05)。结论新发脑梗死后患者均会出现不同程度认知损害及抑郁的情况,存在抑郁的患者认知损害情况更显著,呈交互影响。
[Abstract]:Objective to investigate the relationship between depression and cognitive impairment in patients with newly diagnosed cerebral infarction. Methods 83 patients who were admitted to Department of Neurology, Xinglin Branch, first affiliated Hospital of Xiamen University from February 2015 to January 2017 were selected. Case of new cerebral infarction. Hamilton Depression scale (Hamd), self rating Depression scale (SDS), simple Mental State scale (MMSE) and elderly Depression scale (GDSs) were used for 4 weeks. Patients were divided into depression group and non-depression group according to HAMD score. The patients were divided into three groups: no cognitive impairment group, mild cognitive impairment group and severe cognitive impairment group. The GDS scores of MMSE were significantly higher than those of mild cognitive impairment group and no cognitive impairment group (P 0.05). The MMSESDS score of depression group was higher than that of non-depression group. Conclusion the patients with new cerebral infarction will have different degree of cognitive impairment and depression. The cognitive impairment of patients with depression is more significant and has an interactive effect.
【作者单位】：厦门大学附属第一医院杏林分院神经内科;
【分类号】：R743.33
【正文快照】： 作者单位:361022福建省厦门市,厦门大学附属第一医院杏林分院神经内科脑梗死又称“缺血性脑卒中”(cerebral stroke),中医称为“中风”,好发于中老年人群,是临床常见的脑血管疾病[1]。此病主要由脑梗死或血管阻塞导致血液不能流入大脑而引起脑组织损伤,易引起脑组织缺血低氧性

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