早期高压氧治疗对动脉瘤术后患者康复的临床疗效观察

发布时间：2018-04-10 10:35

本文选题：颅内动脉瘤　+ 高压氧　；引自：《中华肿瘤防治杂志》2016年S1期

【摘要】：目的探讨早期高压氧(hyperbaric oxygen,HBO)治疗对颅内动脉瘤术后患者康复的临床疗效。方法将2010-01-2015-12青州市人民医院神经外科住院的颅内动脉瘤患者67例随机分为对照组和HBO组,对照组予以常规药物和康复治疗,HBO组除常规药物和康复治疗外加用早期HBO治疗,观察两组患者治疗前后脑血流速度、大脑中动脉痉挛情况、临床疗效、神经功能缺损(neurologic function impairment,NFI)评分、日常生活活动能力(activities of daily living,ADL)评估和认知功能(minimum mental state examination,MMSE)评分,ADL评估应用Barthel评分。结果治疗后两组患者的脑血流速度均降低,大脑中动脉痉挛情况好转,NFI评分降低、Barthel评分和MMSE评分均升高,HBO治疗组各项指标改善情况均优于对照组,差异均有统计学意义。结论术后早期运用HBO综合治疗,可促进颅内动脉瘤患者术后脑功能康复,HBO对颅内动脉瘤患者术后脑功能康复有较好的临床疗效。
[Abstract]:Objective to investigate the clinical effect of early hyperbaric oxygenation HBO (HBO) on postoperative patients with intracranial aneurysms.Methods Sixty-seven patients with intracranial aneurysms hospitalized in neurosurgery department of Qingzhou people's Hospital from January to December 2010 were randomly divided into two groups: control group and HBO group. The control group was treated with routine drugs and rehabilitation plus early HBO.Cerebral blood flow velocity, spasm of middle cerebral artery, clinical efficacy, neurologic function impairment (NFI) score, activities of daily livingl (ADL) and cognitive function minimum mental state examination (MMSE) were measured before and after treatment.Results after treatment, the cerebral blood flow velocities of the two groups were all decreased, the middle cerebral artery spasm was improved, and the scores of Barthel and MMSE were increased. The improvement of all indexes in the treatment group was better than that in the control group, and the difference was statistically significant.Conclusion the early application of HBO in the treatment of intracranial aneurysms can promote the rehabilitation of brain function in patients with intracranial aneurysms. It has a good clinical effect on the rehabilitation of brain function in patients with intracranial aneurysms.
【作者单位】：青州市人民医院;
【分类号】：R743

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