急性脑梗死患者血小板微颗粒水平及血小板聚集率的相关性研究

发布时间：2018-06-15 08:00

  本文选题：脑梗死 + 血小板聚集　； 参考：《中华老年心脑血管病杂志》2016年12期

【摘要】：目的研究急性脑梗死(acute ischemic stroke,AIS)患者血清血小板微颗粒(platelet microparticle,PMP)和血小板聚集率(platelet aggregation rate,PAG)与脑梗死预后的关系。方法连续收集2015年1月~2016年1月在我院接受治疗的102例患者,其中男性56例,女性46例,平均年龄(67.81±5.68)岁。AIS组62例,对照组为40例。结果 AIS组PMP[(6.11±1.54)%vs(2.31±0.83)%,P=0.000]和PAG[(81.66±7.15)%vs(57.36±7.98)%,P=0.000]水平较对照组均明显升高。AIS组治疗2周后PMP[(4.28±1.31)%vs(6.11±1.54)%,P=0.000]和PAG[(68.78±7.49)%vs(81.66±7.15)%,P=0.000]水平均较治疗前明显下降。AIS组患者PMP与PAG水平呈显著正相关(r=0.263,P=0.037)。logistic分析显示,年龄、PMP、PAG、TC、空腹血糖与AIS预后相关。结论 PMP和PAG可作为检测判断AIS治疗效果及脑梗死预后的指标。
[Abstract]:Objective to study the relationship between the prognosis of acute cerebral infarction (AIS) and the serum platelet microparticle (PMP), platelet aggregation rate (PLP) and platelet aggregation rate (PMP) in patients with acute cerebral infarction (AIS). Methods 102 patients received treatment in our hospital from January 2015 to January 2016, including 56 males and 46 females, with an average age of 67.81 卤5.68 years old, 62 cases in AIS group and 40 cases in control group. 缁撴灉 AIS缁凱MP[(6.11卤1.54)%vs(2.31卤0.83)%,P=0.000]鍜孭AG[(81.66卤7.15)%vs(57.36卤7.98)%,P=0.000]姘村钩杈冨�圭収缁勫潎鏄庢樉鍗囬�，

本文编号：2021314