房颤脑栓塞患者脑微出血相关危险因素分析

发布时间：2018-12-18 16:46

【摘要】：目的 :运用头颅MRI磁敏感加权成像(susceptibility weighted imaging,SWI)对房颤脑栓塞患者进行检测,探讨房颤脑栓塞患者脑微出血(cerebral microbleeds,CMBs)相关危险因素。方法:对房颤脑栓塞患者72例进行1.5T磁共振扫描(SWI),检测脑微出血的发生率,评价CMBs相关危险因素。结果:轻度脑栓塞34例中,微出血无14例(41.2%),轻度17例(50.0%),中度3例(8.8%),重度0例。中度脑栓塞34例中,微出血无12例(40.0%),轻度15例(50.0%),中度3例(10.0%),重度0例。重度脑栓塞8例中,微出血无2例(25.0%),轻度4例(50.0%),中度1例(12.5%),重度1例(12.5%)。CMBs严重程度与脑栓塞的严重程度无相关性(r=0.142,P=0.081),房颤脑栓塞CMBs与高胆固醇血症、高血压、颈动脉斑块以及抗栓药物的使用相关(P0.05)。结论:房颤脑栓塞患者CMBs相关的危险因素为高胆固醇血症、高血压、颈动脉斑块以及抗栓药物的使用。
[Abstract]:Objective: to investigate the risk factors of cerebral microhemorrhage (cerebral microbleeds,CMBs) in patients with atrial fibrillation and cerebral embolism (ACE) by MRI magnetic sensitivity weighted imaging (susceptibility weighted imaging,SWI). Methods: the incidence of microhemorrhage in 72 patients with atrial fibrillation cerebral embolism (ACE) was detected by 1.5T magnetic resonance scanning (SWI),) and the risk factors related to CMBs were evaluated. Results: in 34 cases of mild cerebral embolism, there were no microhemorrhage in 14 cases (41.2%), mild in 17 cases (50.0%), moderate in 3 cases (8.8%) and severe in 0 cases. In 34 cases of moderate cerebral embolism, there were no microhemorrhage in 12 cases (40.0%), mild in 15 cases (50.0%), moderate in 3 cases (10.0%) and severe in 0 cases. In 8 cases of severe cerebral embolism, there were no microhemorrhage in 2 cases (25.0%), mild in 4 cases (50.0%), moderate in 1 case (12.5%). There was no correlation between the severity of). CMBs and the severity of cerebral embolism in 1 case (12.5%) (r = 0.142). The CMBs of atrial fibrillation and cerebral embolism was associated with hypercholesterolemia and hypertension. Carotid plaque and the use of antithrombotic drugs were related (P0.05). Conclusion: the risk factors associated with CMBs in patients with atrial fibrillation and cerebral embolism are hypercholesterolemia, hypertension, carotid plaque and use of antithrombotic drugs.
【作者单位】：海安县人民医院神经内科;
【分类号】：R743.34

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