聚乙烯乙醇水化海藻盐泡沫创面敷料封闭负压引流修复糖尿病足溃疡

发布时间：2017-12-26 21:41

本文关键词：聚乙烯乙醇水化海藻盐泡沫创面敷料封闭负压引流修复糖尿病足溃疡　出处：《中国组织工程研究》2015年52期 　论文类型：期刊论文

【摘要】：背景:生物敷料封闭负压引流可促进急、慢性创面愈合。目的:观察采用生物敷料封闭负压引流修复糖尿病足溃疡的临床效果。方法:纳入糖尿病足溃疡患者40例,予以清创或清创植皮后,根据患者意愿选择创面治疗方式,试验组(n=20)进行聚乙烯乙醇水化海藻盐泡沫创面敷料封闭负压引流治疗,对照组(n=20)进行常规伤口换药治疗。修复7 d时,对比两组目测类比评分、血沉、C-反应蛋白水平;对比两组创面愈合时间、治疗终止时的患者满意度及经济费用。结果与结论:试验组目测类比评分、血沉、C-反应蛋白水平均低于对照组(P均0.05)。试验组创面愈合时间短于对照组(P0.05),患者满意度高于对照组(P0.05),两组间经济费用比较差异无显著性意义;试验组未发生局部或全身毒性、过敏等不良反应。表明采用聚乙烯乙醇水化海藻盐泡沫创面敷料封闭负压引流修复糖尿病足溃疡安全有效,可促进创面愈合,降低局部炎症反应。
[Abstract]:Background: closed negative pressure drainage of biological dressings can promote the healing of acute and chronic wounds. Objective: To observe the clinical effect of biological dressing closed negative pressure drainage for the repair of diabetic foot ulcers. Methods: a total of 40 cases of diabetic foot ulcer patients, debridement or debridement and skin grafting after wound treatment according to the wishes of patients, the test group (n=20) of polyvinyl alcohol hydration seaweed salt foam dressing vacuum sealing drainage treatment, the control group (n=20) routine wound treatment. When repairing 7 d, we compared two groups of visual analogue scale, erythrocyte sedimentation rate and C- reactive protein level, compared two groups of wound healing time, patients' satisfaction and economic cost at the end of treatment. Results and conclusion: the visual analogue score, erythrocyte sedimentation rate and C- reactive protein level in the experimental group were lower than those in the control group (P 0.05). The wound healing time in the experimental group was shorter than that in the control group (P0.05), and the satisfaction degree of the patients in the experimental group was higher than that in the control group (P0.05). There was no significant difference in the economic cost between the two groups, and there was no local or systemic toxicity or allergy in the test group. The results showed that polyethylene glycol hydration, alginate foam wound dressing and vacuum sealing drainage were effective and safe in the treatment of diabetic foot ulcers, which could promote wound healing and reduce local inflammatory response.
【作者单位】：解放军南京军区总医院骨科;解放军南京军区南京总医院汤山分院护理部;
【分类号】：R318.08
【正文快照】： 0引言Introduction中男21例,女19例,Wanger分级Ⅰ-Ⅲ级,根据患者意愿糖尿病足是由于糖尿病病程损伤至血管、神经及诱发选择采用生物敷料创面敷料封闭负压引流治疗或常规伤口感染的局部因素等联合作用造成的足或下肢组织破坏,是换药治疗方案进行治疗。设定采用生物材料创面敷料

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