纳米金胶体的制备及其对血液光吸收性的影响

发布时间：2018-03-06 05:21

本文选题：医用光学　切入点：纳米金　出处：《中国激光》2015年06期 　论文类型：期刊论文

【摘要】：纳米金是指粒径介于1~100 nm之间的金粒子,具有良好的生物兼容性、结构稳定性和光学性质,可用于强化激光治疗血管性皮肤病的光吸收。采用柠檬酸钠还原法制备纳米金胶体,研究了温度、加热时间、柠檬酸钠还原剂用量等因素对其粒径和吸收光谱的影响,得到了制备纳米金胶体的最佳条件。取制备得到的粒径为16 nm左右的纳米金胶体与血液混合后稀释,研究了胶体金对血液光吸收性能的影响及其随温度的变化规律。结果表明,加入胶体金后血液的光吸收性能随着加入体积比的增大而增强,当胶体金与血液的体积比为5时,血液在545 nm和581 nm处的吸收峰值分别提高了1.33倍和1.09倍。在变温条件下,胶体金不会对血液的动态吸收特性产生影响。
[Abstract]:Nanocrystalline gold is a gold particle with a diameter between 1 ~ 100 nm, which has good biological compatibility, structural stability and optical properties. It can be used to enhance the absorption of light in the treatment of vascular dermatosis by laser. The gold colloid is prepared by sodium citrate reduction method. The effects of temperature, heating time and the amount of sodium citrate reducing agent on the particle size and absorption spectrum were studied. The optimum conditions for the preparation of gold nanoparticles were obtained. The effects of gold colloids on the photoabsorption properties of blood and their changes with temperature were studied by diluting the gold colloids with the particle size of about 16 nm. When the volume ratio of colloidal gold to blood is 5:00, the absorption peak at 545 nm and 581 nm increases by 1.33 times and 1.09 times, respectively, when the volume ratio of colloidal gold to blood increases by 1.33 and 1.09 times, respectively, when the volume ratio of colloidal gold to blood increases by 1.33 and 1.09 times, respectively, when the volume ratio of colloidal gold to blood is 5:00, Colloidal gold does not affect the dynamic absorption of blood.
【作者单位】：西安交通大学动力工程多相流国家重点实验室;阿克伦大学机械工程系;
【基金】：国家自然科学基金(51336006) 陕西省国际科技合作与交流计划(2013KW30-05) 中央高校基本科研业务费专项资金
【分类号】：R318.08

【共引文献】