右美托咪定复合布托啡诺对脊柱后路手术术后镇痛的影响

发布时间：2017-12-27 03:36

本文关键词：右美托咪定复合布托啡诺对脊柱后路手术术后镇痛的影响　出处：《医学与哲学(B)》2016年11期 　论文类型：期刊论文

【摘要】：观察右美托咪定复合布托啡诺用于脊柱后路手术术后患者静脉自控镇痛的安全性和有效性。60例行脊柱后路内固定手术的患者,随机分为2组,术后镇痛分别给予布托啡诺0.125mg/kg组(B组)、右美托咪定0.1μg/kg/h+布托啡诺0.125mg/kg组(DB组)。两组患者在术后不同时间点安静和活动时的VAS评分相互比较差异有统计学意义(P0.05),DB组疼痛感觉较B组轻;DB组的镇静评分在术后1h(T_1)、2h(T_2)、6h(T_3)和12h(T_4)时高于B组,但差异无统计学意义(P0.05);DB组的按压次数少于B组(P0.05);与B组相比较,DB组恶心的发生率降低(P0.05);术后DB组总的满意度高于B组(P0.05)。右美托咪定可增强布托啡诺对脊柱后路手术患者的术后镇痛效果,减少布托啡诺消耗量,降低不良反应发生率,提高患者满意度。
[Abstract]:To observe the safety and efficacy of dexmedetomidine combined with Bhutto enphanol for intravenous self controlled analgesia after posterior spinal surgery. Patients with internal fixation of spine after operation in 60 cases, were randomly divided into 2 groups, postoperative analgesia were given Bhutto butorphanol 0.125mg/kg group (group B), dexmedetomidine 0.1 g/kg/h+ Bhutto 0.125mg/kg butorphanol group (group DB). There was statistical significance in VAS at different time point after quiet and activities of the scores of the two groups compare difference (P0.05), DB group pain than B group; group DB sedation score in postoperative 1H (T_1), 2h (T_2), 6h (T_3) and 12h (T_4) is higher than the in B group, but the difference was not statistically significant (P0.05); press the number in DB group than in the B group (P0.05); compared with B group, DB group reduced the incidence of nausea (P0.05); group DB total satisfaction is higher than that of B group (P0.05). Dexmedetomidine can enhance the analgesic effect of Bhutto in postoperative patients after spinal surgery, reduce the consumption of Bhutto, reduce the incidence of adverse reactions and improve patient satisfaction.
【作者单位】：锦州医科大学附属第一医院;
【分类号】：R614
【正文快照】： 1锦州医科大学附属第一医院辽宁锦州121001脊柱后路手术具有时间长、出血量大、术中术后刺激强等特点,对术后镇痛要求比较高,因此大量的阿片类药物被用于术后镇痛,阿片类药物量需求的增多,势必会引起不良反应如嗜睡、恶心、呕吐等,而多模式镇痛大大减少了单纯大剂量阿片类药物

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