机械瓣或生物瓣对治疗感染性心内膜炎安全性和有效性影响的Meta分析

发布时间：2017-12-28 11:05

本文关键词：机械瓣或生物瓣对治疗感染性心内膜炎安全性和有效性影响的Meta分析　出处：《实用医学杂志》2016年22期 　论文类型：期刊论文

【摘要】：目的:应用Meta分析的方法评价生物瓣和机械瓣对治疗感染性心内膜炎安全性和有效性的影响。方法:通过计算机检索国内外几个主要文献数据库(Pubmed、Medline、The Cochrance Library、Embase、CNKI、万方、CBM),获得目前已经公开发表的有关选用机械瓣和生物瓣治疗感染性心内膜炎的相关文献。经筛选文献、质量评估后,运用Rev Man 5.3对所得数据进行Meta分析。结果:使用机械瓣治疗感染性心内膜炎组在手术近期病死率(P=0.001)、术后5年存活率(P=0.003)及术后再感染率(P=0.003)等方面均优于使用生物瓣组,差异有统计学意义。结论:在院内病死率、5年存活率及术后再感染率等方面,治疗感染性心内膜炎时选择机械瓣均优于使用生物瓣。
[Abstract]:Objective: To evaluate the effect of biological and mechanical valves on the safety and effectiveness of infective endocarditis with Meta analysis. Methods: a number of main literature databases at home and abroad (Pubmed, Medline, The Cochrance Library, Embase, CNKI, Wan Fang and CBM) were retrieved by computer. After screening literature and quality evaluation, Rev Man 5.3 was used to analyze the data obtained by Meta. Results: the short-term mortality rate (P=0.001), postoperative 5 year survival rate (P=0.003) and postoperative reinfection rate (P=0.003) in mechanical infective endocarditis group were better than those in the bioprosthetic group, and the difference was statistically significant. Conclusion: the selection of mechanical valves in the treatment of infective endocarditis is better than that of the biological valve in the treatment of infective endocarditis, such as the mortality rate, the 5 year survival rate and the rate of reinfection after operation.
【作者单位】：川北医学院附属医院胸心外科;川北医学院预防医学系;
【分类号】：R654.2
【正文快照】： 随着药物治疗和心脏外科手术技术的发展,感染性心内膜炎(infective endocarditis,IE)患者的病死率和并发症发生率已经大大降低。手术所起的重要作用得到越来越多的外科医生的重视。如果IE患者心脏瓣膜损坏轻,瓣膜修复被认为是最好的方法[1];而就诊的IE患者通常瓣膜损坏严重,多

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