金叶败毒颗粒辅助治疗烧伤脓毒症的临床效果研究

发布时间：2018-01-04 20:07

  本文关键词：金叶败毒颗粒辅助治疗烧伤脓毒症的临床效果研究　出处：《中药药理与临床》2016年06期 　论文类型：期刊论文

  更多相关文章： 金叶败毒颗粒 脓毒症 炎症因子 肾脏功能

【摘要】：目的:观察金叶败毒颗粒佐治烧伤脓毒症的临床效果。方法:选取2013年2月至2014年2月我科室收治的烧伤并发脓毒症患者45例,按随机双盲法将其分为对照组22例和观察组23例。对照组给予常规治疗,观察组在对照组基础上加用金叶败毒颗粒。记录并分析治疗前和治疗后10天两组患者体温、心率、白细胞、中性粒细胞、血尿素氮、血肌酐、肿瘤坏死因子(TNF-α)和白细胞介素-8(IL-8)的水平变化情况。结果:治疗后观察组患者体温、心率分别为(37.2±0.4℃、85.5±5.1次/分),均明显低于对照组(38.2±0.6℃、103.8±7.5次/分);观察组治疗后白细胞和中性粒细胞分别为(7.96±2.34×109/L、55.76±5.83%),均明显低于对照组(14.28±3.61×109/L、69.46±7.15%);3观察组治疗后血尿素氮和血肌酐分别为(7.4±0.6mmol/L、90.1±2.2μmol/L),均明显低于对照组(9.2±1.0mmol/L、95.7±3.3μmol/L);4观察组治疗后TNF-α和IL-8分别为(3.15±0.71ng/ml、3.01±0.42ng/ml),均明显低于对照组(5.01±0.83ng/ml、4.19±0.53ng/ml)。结论:金叶败毒颗粒可调节烧伤脓毒症患者的体温和心率,维护肾脏功能,降低患者体内炎症水平。
[Abstract]:Objective: to observe the clinical effect of Jinye Baidu granule in treating burn sepsis. Methods: from February 2013 to February 2014, 45 burn patients with sepsis were selected. It was divided into control group (22 cases) and observation group (23 cases) according to random double blind method. The control group was given routine treatment. The observation group was treated with Jinye Baidu granule on the basis of the control group. The body temperature, heart rate, leukocyte, neutrophil, blood urea nitrogen and serum creatinine were recorded and analyzed before and 10 days after treatment. Results: after treatment, the temperature and heart rate of the patients in the observation group were 37.2 卤0.4 鈩，

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