低危腹腔镜腹股沟疝修补术使用预防性抗生素的前瞻性研究

发布时间：2018-01-13 18:38

本文关键词：低危腹腔镜腹股沟疝修补术使用预防性抗生素的前瞻性研究　出处：《中华疝和腹壁外科杂志(电子版)》2016年06期 　论文类型：期刊论文

【摘要】：目的探讨腹股沟疝患者行腹腔镜腹膜前腹股沟疝修补术是否需要使用预防性抗生素。方法按照随机双盲法,前瞻性研究分析2015年5~12月,上海市东方医院200例腹腔镜下腹膜前腹股沟疝修补手术患者的临床资料,每组患者100例。非使用预防性生素组(试验组)术前30 min仅给予0.5%氯化钠溶液100 ml静脉滴注,而使用预防性抗生素组(对照组)术前30 min给予头孢唑林钠2 g+0.5%氯化钠溶液100 ml静脉滴注。结果术中1例TEP中转TAPP,1例TAPP中转开放,术后15例失访。最终入组183例,入组率91.5%,其中试验组89例(89%),对照组94例(94%)。2组患者在手术部位感染、术后发热、血清肿和血肿的发生率上差异均无统计学意义(χ2=0.000、0.002、0.688、0.002,P=1.000、0.962、0.407、0.962)。结论对于低危腹腔镜腹膜前腹股沟疝修补术,没有必要使用抗生素预防术后手术部位感染,不使用预防性抗生素也不会增加术后发热、血肿或血清肿的发生率。
[Abstract]:Objective to investigate the need of prophylactic antibiotics for laparoscopic preperitoneal hernia repair in patients with inguinal hernia. Clinical data of 200 patients undergoing laparoscopic anterior inguinal hernia repair in Oriental Hospital of Shanghai. One hundred patients in each group were given only 100ml sodium chloride solution 30 min before operation in the non-use preventive biotin group (trial group). The preventive antibiotic group (control group) was given cefazolin sodium 2 g 0.5% sodium chloride solution 100ml intravenous drip 30 min before operation. Results one case of TEP was transferred to TAPP during the operation. One case of TAPP was turned to open, 15 cases lost the visit after operation. Finally, 183 cases were admitted into the group, the rate of entry was 91.5%, of which 89 cases were in the test group (89 cases). There was no significant difference in the incidence of infection, fever, serum swelling and hematoma in 94 patients in the control group (蠂 2 + 0.000 卤0.002). Conclusion low risk laparoscopic preperitoneal inguinal hernioplasty was performed. There is no need to use antibiotics to prevent postoperative site infection, and no use of prophylactic antibiotics does not increase the incidence of postoperative fever, hematoma or serum swelling.
【作者单位】：上海市东方医院疝与腹壁外科;
【分类号】：R656.21
【正文快照】： 腹腔镜下腹股沟疝修补术(laparoscopic inguinalhernia repair,LIHR)在国内已经得到越来越多的应用,其中最有代表性的就是经腹腹膜前疝修补术(trans-abdominal pre-peritoneal,TAPP)和完全腹膜作者单位:200120上海市东方医院疝与腹壁外科外疝修补术(totally extra-peritoneal,

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