神经外科患者医院获得性肺炎危险因素的Meta分析

发布时间：2018-01-20 10:40

本文关键词： 神经外科医院获得性肺炎危险因素 Meta分析　出处：《中国感染控制杂志》2017年05期 　论文类型：期刊论文

【摘要】：目的系统评价神经外科患者医院获得性肺炎的危险因素。方法检索2001—2016年国内外已发表的有关国内神经外科患者医院获得性肺炎危险因素的文献,选择符合标准的临床研究资料进行Meta分析,计算每个因素的合并OR值。结果总共7篇文献纳入研究,累计研究对象3 250例。排除发表偏倚的可能,共有8个因素有统计学意义,分别为年龄(OR=1.68,95%CI:1.16~2.11)、气管插管或切开(OR=11.31,95%CI:9.14~13.63)、意识障碍(OR=12.74,95%CI:10.63~15.91)、住院日数(OR=2.36,95%CI:1.42~4.81)、基础疾病(OR=3.17,95%CI:2.18~5.24)、使用呼吸机(OR=2.38,95%CI:1.56~4.32)、营养状况(OR=4.92,95%CI:2.69~6.47)、侵入性操作(OR=2.13,95%CI:1.34~3.86)。结论年龄、气管插管或切开、意识障碍、住院日数、基础疾病、使用呼吸机、营养状况、侵入性操作神经外科医院获得性肺炎的危险因素,而吸烟、性别、手术类型尚不能确定为神经外科医院获得性肺炎的危险因素。
[Abstract]:Objective to systematically evaluate the risk factors of nosocomial pneumonia in neurosurgical patients. Methods the literature on the risk factors of nosocomial pneumonia of neurosurgical patients in China and abroad from 2001 to 2016 was searched. . Meta analysis was performed on clinical data that met the criteria. The combined OR value of each factor was calculated. Results A total of 7 articles were included in the study. A total of 3 250 subjects were included. Excluding the possibility of publication bias, there were 8 factors with statistical significance, namely, the age of 1.6895 CI: 1.162.11). Trachea intubation or incision: 11.31 / 95 CI: 9.14 ~ 13.63%, disorder of consciousness 12.74 / 95 CI: 10.63 / 15.91). The number of days spent in the hospital was 2.36 / 95 / CI: 1.422 / 4.81, and the basic illness was 3.17 / 95 / CI: 2.185.24). Use a ventilator: 2.3895 CI: 1.56 / 4.32, nutritional status: 4.92 / 95 CI: 2.69 / 6.47). The invasive operation was 2.1395% CI: 1.34 / 3.860.Conclusion Age, tracheal intubation or incision, disturbance of consciousness, number of days in hospital, basic diseases, use of ventilator, nutritional status. The risk factors of nosocomial pneumonia in invasive neurosurgery, while smoking, sex and type of surgery can not be identified as the risk factors of nosocomial pneumonia in neurosurgery.
【作者单位】：邢台市第三医院;
【分类号】：R563.1;R651
【正文快照】： 下呼吸道感染是神经外科住院患者的严重并发症[1],在感染部位中占首位,严重的下呼吸道感染极易诱发患者呼吸障碍,甚至全身感染;且致病菌多为耐药菌,治疗难度较大,发病率及病死率较高[2]。为更好地研究神经外科医院获得性肺炎的危险因素,本研究对国内已发表文献的研究结果进行M

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