右美托咪定复合瑞芬太尼在心房颤动经导管射频消融术中的应用

发布时间：2018-01-24 17:58

本文关键词： 右美托咪定瑞芬太尼房颤射频消融术　出处：《广东医学》2017年19期 　论文类型：期刊论文

【摘要】：目的探讨右美托咪定复合瑞芬太尼静脉恒速输注用于心房颤动(房颤)导管射频消融术中镇静和镇痛的效果。方法选择行房颤导管射频消融术患者80例,用随机数字表法分为右美托咪定复合瑞芬太尼组(DR组)和瑞芬太尼组(R组)。DR组在手术开始前10 min输注右美托咪定1μg/kg,10 min泵完,随后以0.3μg/(kg·h)持续泵注至手术结束。R组输注等量生理盐水。手术前两组患者均静脉持续泵注瑞芬太尼0.05μg/(kg·min)。记录入手术室时(T0)、手术开始后10 min(T1)、30 min(T2)、60 min(T3)、120 min(T4)及术毕(T5)时的平均动脉压、心率、呼吸、血氧饱和度和Ramsay镇静评分。同时记录两组患者术中追加瑞芬太尼的剂量、停药后清醒时间、患者和手术医师的满意度以及术中不良事件的发生率。结果 DR组的Ramsay镇静评分在手术后各时间点明显高于R组(P0.05);术中追加的瑞芬太尼的剂量明显低于R组(P0.05);患者的满意度评分和手术医师的满意度评分明显高于R组(P0.05)。DR组心率减慢的发生率为12.5%,R组未观察到心率减慢的发生。结论右美托咪定复合瑞芬太尼静脉恒速输注用于房颤导管射频消融术具有较好的镇静和镇痛效果、更好的患者和手术医师满意度。
[Abstract]:Objective to investigate the effect of intravenous intravenous infusion of dexmetomidine and remifentanil on sedation and analgesia in atrial fibrillation (AF) catheter radiofrequency ablation. Methods 80 patients with atrial fibrillation catheter radiofrequency ablation were selected. The patients were randomly divided into two groups: dexmetomidine combined with remifentanil group (Dr group) and remifentanil group (group R). Dexmetomidine 1 渭 g / kg was infused 10 min before operation. 10 min pump finished. After that, 0.3 渭 g / kg 路h of remifentanil was continuously pumped to the end of operation. Group R was infused with the same amount of normal saline. Before the operation, remifentanil 0.05 渭 g / kg 路min was continuously injected intravenously in both groups. ... recorded in the operating room (T0). The mean arterial pressure, heart rate and respiration were measured 10 min after operation and 30 min after operation. Blood oxygen saturation and Ramsay sedation score. The dosage of remifentanil was recorded in both groups, and the waking time after withdrawal was recorded. Results the Ramsay sedation score of Dr group was significantly higher than that of R group at each time point (P 0.05). The dose of remifentanil added during operation was significantly lower than that in group R (P 0.05). The patients' satisfaction score and the surgeon's satisfaction score were significantly higher than that of R group (P 0.05). Dr group had a lower rate of heart rate (12.5%). Conclusion right metoimidine combined with remifentanil has a good sedative and analgesic effect in atrial fibrillation catheter radiofrequency ablation. Better patient and surgeon satisfaction.
【作者单位】：南昌大学第二附属医院麻醉科;
【分类号】：R614
【正文快照】： 导管射频消融术现已成为心房颤动(房颤)的瑞芬太尼用于导管射频消融术麻醉的临床效果。主要治疗手段之一,但这类手术疼痛非常剧烈,易导1资料与方法致患者产生焦虑和肢体移动,术中焦虑和疼痛也成1.1一般资料本研究已获本院医学伦理委员会为影响手术操作的常见原因[1-2]。而这类

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