肝硬化失代偿期患者并发肠梗阻的临床特点及相关危险因素分析

发布时间：2018-01-24 21:05

  本文关键词： 肝硬化 肠梗阻 临床特征 危险因素　出处：《上海交通大学学报(医学版)》2017年07期 　论文类型：期刊论文

【摘要】：目的·分析肝硬化失代偿期患者并发肠梗阻的临床特点及危险因素。方法·收集2010年3月—2016年3月收治的1 783例肝硬化失代偿期患者的临床资料,筛选出并发肠梗阻患者128例(7.18%)作为观察组,随机抽取未并发肠梗阻患者128例作为对照组。回顾性研究2组患者的临床资料,对临床特征进行对比分析,并采用Logistic回归分析相关危险因素。结果·肝硬化失代偿期患者并发肠梗阻的临床症状隐匿,容易被漏诊或延迟诊断。观察组腹痛、腹胀、呕吐、停止排便排气、发热、自发性腹膜炎、腹水、电解质紊乱的发生率显著高于对照组(P0.05)。单因素分析结果显示:年龄、腹部手术史、白细胞计数、血清钾、血清钠、中性粒细胞百分比、血清白蛋白为肝硬化失代偿期患者并发肠梗阻的危险因素。进一步的多因素回归分析结果显示:年龄、腹部手术史、白细胞计数、血清钾、血清钠、中性粒细胞百分比、血清白蛋白是肝硬化失代偿期患者并发肠梗阻的独立危险因素。结论·年龄≥50岁、有腹部手术史、合并腹腔感染、低钾、低钠、低血清白蛋白的肝硬化失代偿期患者容易并发肠梗阻。
[Abstract]:Objective: to analyze the clinical characteristics and risk factors of intestinal obstruction in patients with decompensated cirrhosis from March 2010 to March 2016. Clinical data of 783 patients with decompensated cirrhosis. 128 patients with intestinal obstruction were selected as observation group, 128 patients without intestinal obstruction were randomly selected as control group. The clinical data of two groups were studied retrospectively. The clinical features were compared and analyzed, and Logistic regression analysis was used to analyze the risk factors. Results: the clinical symptoms of intestinal obstruction in patients with decompensated cirrhosis were hidden. Easy to be missed or delayed diagnosis. Observation group abdominal pain, abdominal distension, vomiting, stop defecation and exhaust, fever, spontaneous peritonitis, ascites. The incidence of electrolyte disturbance was significantly higher than that of control group (P 0.05). Univariate analysis showed that age, history of abdominal surgery, white blood cell count, serum potassium, serum sodium, percentage of neutrophils. Further multivariate regression analysis showed that age, history of abdominal surgery, leukocyte count, serum potassium, serum sodium. Percentage of neutrophils and serum albumin were independent risk factors of intestinal obstruction in patients with decompensated cirrhosis. Conclusion: age 鈮，

本文编号：1461015