右美托咪定联合降压药对DebakeyⅠ型主动脉夹层疗效的观察

发布时间：2018-01-25 00:27

  本文关键词： 主动脉夹层 右美托咪定 降压药 疗效　出处：《中华高血压杂志》2017年02期 　论文类型：期刊论文

【摘要】：目的探讨右美托咪定(Dex)联合降压药用于DebakeyⅠ型主动脉夹层患者对术前血压、心率的临床效果。方法收集2013年1月至2016年2月大连医科大学附属第一医院心脏重症监护室所有DebakeyⅠ型主动脉夹层合并高血压患者的临床相关资料,根据Dex的使用情况将患者随机分为非Dex组(Non-Dex组,常规降压药物)和Dex组(常规药物+静脉泵注Dex),各26例。观察患者降压药物治疗期间心率、血压等临床指标,比较两组患者药物使用情况及疗效。结果与Non-Dex组比较,Dex组在不同时间段使用硝普钠、乌拉地尔、硝苯地平、艾司洛尔、美托洛尔、替米沙坦等降压药物剂量明显减少(P0.05);平均动脉压(MAP)及心率降低(均P0.05);6h内Dex组MAP、心率达标率分别为76.92%、80.77%,明显高于Non-Dex组(均P0.05)。结论 Dex联合降压药用于DebakeyⅠ型主动脉夹层患者,可明显减少服用降压药剂量,有效控制血压、心率,缩短目标血压、心率达标时间,提高达标率。
[Abstract]:Objective to investigate the preoperative blood pressure of patients with Debakey type I aortic dissection treated with dexmetomidine combined with antihypertensive drugs. Methods the clinical effects of heart rate were collected from January 2013 to February 2016 in all patients with Debakey type I aortic dissection complicated with hypertension in Cardiac intensive Care Unit of the first affiliated Hospital of Dalian Medical University. Clinical data. According to the use of Dex, the patients were randomly divided into non-Dex group (non-Dex group, conventional antihypertensive drug) group and Dex group (Dexx group). The clinical indexes such as heart rate and blood pressure were observed and compared between the two groups. The results were compared with those in the Non-Dex group. The dosage of sodium nitroprusside, urapidil, nifedipine, esmolol, metoprolol and telmisartan were significantly decreased in Dex group. The mean arterial pressure (MAPP) and heart rate (P 0.05) were decreased. Within 6 hours, the rate of Dex and heart rate were 76.92% and 80.77%, respectively. Conclusion Dex combined with antihypertensive drugs can significantly reduce the dosage of antihypertensive drugs in patients with Debakey type 鈪，

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