短波紫外线照射辅助治疗烧伤后残余创面的效果观察

发布时间：2018-01-25 09:14

本文关键词： 烧伤残余创面紫外线治疗仪重组人粒细胞巨噬细胞集落刺激因子凝胶　出处：《广东医学》2017年16期 　论文类型：期刊论文

【摘要】：目的观察短波紫外线治疗仪联合外用重组人粒细胞巨噬细胞集落刺激因子凝胶(rh GM-CSF)在治疗烧伤残余创面中的疗效。方法将111例烧伤后治疗1个月仍有残余创面的患者随机分为观察组和对照组。观察组60例,先用短波紫外线治疗仪对残余创面照射20~30 s,再用碘伏消毒创面,外涂rh GM-CSF凝胶;对照组51例,残余创面直接用碘伏消毒后,局部外涂rh GM-CSF凝胶治疗。结果在治疗后第7天和第14天,观察组和对照组的创面愈合率相比,差异有统计学意义(P0.05);在治疗后第10天,观察组的创面细菌清除率明显高于对照组,差异有统计学意义(P0.05)。结论与单用rh GM-CSF相比,紫外线照射治疗联合rh GM-CSF凝胶在治疗烧伤残余创面中疗效显著,可在临床推广。
[Abstract]:Objective to observe the combination of short-wave ultraviolet therapy with recombinant human granulocyte macrophage colony stimulating factor gel rh GM-CSF. Methods 111 patients with residual burn wounds were randomly divided into observation group (n = 60) and control group (n = 60). The residual wounds were irradiated for 20 ~ 30 s with a short-wave ultraviolet therapy instrument, then disinfected with iodophor and then coated with rh GM-CSF gel. There were 51 cases in the control group, the residual wounds were treated with Rh GM-CSF gel directly after iodophor disinfection. Results on the 7th and 14th days after treatment, the healing rate of the wounds in the observation group and the control group was higher than that in the control group. The difference was statistically significant (P 0.05). On the 10th day after treatment, the bacterial clearance rate in the observation group was significantly higher than that in the control group, and the difference was statistically significant (P 0.05). Conclusion compared with Rh GM-CSF alone, the bacterial clearance rate in the observation group was significantly higher than that in the control group. Ultraviolet irradiation combined with rh GM-CSF gel is effective in treating residual burn wounds and can be popularized in clinic.
【作者单位】：中国人民解放军第三军医大学第一附属医院烧伤研究所;
【分类号】：R644
【正文快照】： 烧伤是指物理、化学、热力、辐射等因素造成的皮肤及皮下组织器官的损伤。烧伤是在日常生活中比较常见的重要创伤,我国每年每100万人中就约有5 000~10 000人烧伤[1]。烧伤后皮肤及皮下组织器官完整性和功能受损,易引起感染、残障甚至死亡。创面疼痛、进行性坏死、感染、瘢痕愈

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