消肿洗剂治疗混合痔术后肛缘水肿的临床研究

发布时间：2018-01-26 12:44

本文关键词： 混合痔肛缘水肿消肿洗剂　出处：《南京中医药大学》2017年硕士论文　论文类型：学位论文

【摘要】：目的:通过对消肿洗剂熏洗与50%硫酸镁湿敷、温水坐浴治疗痔术后肛缘水肿的临床效果的比较,验证消肿洗剂治疗痔术后肛缘水肿的临床疗效及其临床安全性。方法:选取南京市中医院肛肠科2016年3月至2016年12月因混合痔入院,同时符合本次临床研究的纳入标准及排除标准的60例患者,随机分为消肿洗剂组、50%硫酸镁组、温水坐浴组,每组各20例。消肿洗剂组于术后第2日起予125ml消肿洗剂原液加开水至1000ml先熏后洗15min,每日2次,连用6日。50%硫酸镁组于术后第2日起予50%硫酸镁溶液湿敷30min,每日2次,连用6日。温水坐浴组于术后第2日起予1000ml开水先熏后洗15min,每日2次,连用6日。分别记录三组治疗前及治疗1日、治疗3日、治疗6日后的水肿体积、疼痛评分、症状评分等,并对消肿洗剂组与50%硫酸镁组、温水坐浴组的数据分别进行统计学分析,若P0.05,则差异有统计学意义。结果:(1)三种治疗方法皆可缓解痔术后肛缘水肿,但消肿洗剂组(总有效率95%)的疗效显著优于50%硫酸镁组(总有效率65%)及温水坐浴组(总有效率40%)(P0.05)。(2)消肿洗剂组的水肿体积及症状评分明显低于50%硫酸镁组、温水坐浴组,且差异有统计学意义(P0.05)。结论:消肿洗剂组治疗混合痔术后肛缘水肿的疗效优于50%硫酸镁组、温水坐浴组。消肿洗剂在治疗过程中未出现毒副反应,具有良好的药物安全性。
[Abstract]:Objective: to compare the clinical effect of fumigation and washing with 50% magnesium sulfate and warm water sitting bath in treating anal edema after hemorrhoids operation. Objective: to verify the clinical efficacy and safety of Xiaozhong lotion in the treatment of perianal edema after hemorrhoids. Methods: from March 2016 to December 2016, the anorectal department of Nanjing traditional Chinese Medicine Hospital was admitted to hospital for mixed hemorrhoids. At the same time, 60 patients who met the criteria of inclusion and exclusion in this clinical study were randomly divided into two groups: 50% magnesium sulfate group, 50% magnesium sulfate group and a warm water sitting bath group. In each group, 20 cases were treated with 125ml solution of Xiaozhong lotion for 15 min after fumigation and then washed twice a day from 2nd to 1000ml. The group of 50% magnesium sulfate on 6th was treated with 50% magnesium sulfate solution for 30 minutes, twice a day from 2nd after operation. The warm water sitting bath group was treated with 1000ml boiling water for 15 mins, twice a day, on 6th. The three groups were recorded before and after the treatment of 6th, respectively. After 6 days of treatment, edema volume, pain score, symptom score, and so on, and the swelling lotion group and 50% magnesium sulfate group, warm water sitting bath data were statistically analyzed, if P0.05. Results all three treatments could relieve anal edema after hemorrhoids operation. But the curative effect of Xiaozhong lotion group (total effective rate 95%) was significantly better than that of 50% magnesium sulfate group (total effective rate 65%) and warm water sitting bath group (total effective rate 40). The edema volume and symptom score of Xiaozhong lotion group were significantly lower than that of 50% magnesium sulfate group. Conclusion: the effect of Xiaozhonglotion group on anal edema after mixed hemorrhoids is better than that of 50% magnesium sulfate group. Warm water sitting bath group. Xiaozhong lotion has no toxic and side effects during the treatment, so it has good drug safety.
【学位授予单位】：南京中医药大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R657.18

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