腹腔镜胃袖状切除术对肥胖伴亚临床甲状腺功能减退症的影响

发布时间：2018-01-28 18:05

本文关键词： 亚临床甲状腺功能减退症胃袖状切除术代谢综合征肥胖症　出处：《中国微创外科杂志》2017年10期 　论文类型：期刊论文

【摘要】：目的探讨腹腔镜胃袖状切除术对肥胖伴亚临床甲状腺功能减退症(subclinical hypothyroidism,SCH)的影响。方法回顾性分析2014年7月~2015年6月69例接受腹腔镜胃袖状切除术的肥胖(体重指数26~45.7)患者的临床资料,14例(20.3%)合并SCH(SCH组),另55例(79.7%)未合并SCH(非SCH组)。比较2组术前促甲状腺激素及相关代谢指标,以及SCH组手术前后促甲状腺激素及相关代谢指标。结果术前SCH组57.1%(8例)合并代谢综合征(metabolic syndrome,MS),非SCH组为29.1%(16例);SCH组术前促甲状腺激素(thyroid stimulating hormone,TSH)(6.07±1.68)μIU/ml,术后12个月降至(2.88±0.56)μIU/ml(t=7.113,P=0.000)。结论腹腔镜胃袖状切除术可能促使促甲状腺激素下降,改善肥胖伴SCH。
[Abstract]:Objective to investigate the effect of laparoscopic sleeve gastrectomy on subclinical hypothyroidism of obesity with subclinical hypothyroidism. Methods the clinical data of 69 patients with obesity (BMI 2645.7) undergoing laparoscopic gastrectomy from July 2014 to June 2015 were retrospectively analyzed. There were 14 cases with SCH(SCH and 55 cases with Sch (non-Sch group). The thyroid stimulating hormone (TSH) and related metabolic indexes were compared between the two groups before operation. Results before and after operation, the thyroid stimulating hormone (TSH) and related metabolic indexes were found in SCH group. Results the metabolic syndrome was associated with metabolic syndrome in 8 patients in SCH group before and after operation. In the SCH group, there were 16 cases with musculus in 29. 1%; In SCH group, thyrotropin stimulating hormoney was 6.07 卤1.68 渭 IU/ml before operation. At 12 months after operation, it decreased to 2.88 卤0.56 渭 U / ml / ml ~ (7.113) ~ 0.000 ~ 0.000 渭 U / ml. Conclusion Laparoscopic sleeve gastrectomy may promote the decrease of thyroid stimulating hormone (TSH). To improve the obesity associated with SCH.
【作者单位】：同济大学附属东方医院糖尿病与减重外科;
【分类号】：R581.2;R656.6
【正文快照】： 亚临床甲状腺功能减退症(subclinicalindex,BMI)30~40的病态肥胖者中,约14%合并hypothyroidism,SCH)以血清促甲状腺激素(thyroidSCH,而当BMI超过40时其发生率可上升至25%stimulating hormone,TSH)水平升高为基本特征,血左右[2]。SCH起病隐匿,无明显临床症状,如不及清甲状腺激

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