人工髋关节置换修复老年骨质疏松性股骨颈骨折发生下肢深静脉血栓的时间分布

发布时间：2018-02-01 16:12

本文关键词： 股骨颈骨折关节成形术置换髋骨质疏松静脉血栓形成组织工程骨科植入物人工假体关节成形术深静脉血栓时间分布　出处：《中国组织工程研究》2017年19期 　论文类型：期刊论文

【摘要】：背景:下肢静脉血栓是髋关节置换术后发生率较高的并发症,目前对于老年骨质疏松性股骨颈骨折行关节置换后血栓形成的时间临床研究报道较少。目的:探讨采用人工髋关节置换治疗的老年骨股颈骨折患者围手术期下肢深静脉血栓发生的时间分布。方法:分析178例老年股骨颈骨折行人工髋关节置换治疗患者的资料。患者根据置换前是否应用低分子量肝素抗凝剂分为抗凝组和非抗凝组。所有患者伤后第1,3,5天、伤后5-7 d、术后第2,5,7,14天行双下肢静脉彩超检查对下肢静脉血栓监测,记录和统计不同时间点2组患者发生血栓的例数和发生率,通过绘制频数分布表及折线图确定伤后和术后血栓高发时间点。结果与结论:(1)抗凝组72例共发生血栓6例(8%);未抗凝组106例共发生血栓22例(21%),2组比较差异有显著性意义(P0.05);(2)患者血栓发生时间集中在伤后3 d及术后第1天;(3)结论:股骨颈骨折患者血栓发生的高峰时间是伤后1-3 d及关节置换后第1天,伤后即采取预防措施可显著减少下肢静脉血栓的发生。
[Abstract]:Background: venous thrombosis of lower extremity is a complication of hip arthroplasty. There are few clinical studies on the time of thrombus formation after joint replacement for senile osteoporotic femoral neck fracture. To investigate the time distribution of deep venous thrombosis in lower extremities in elderly patients with femoral neck fracture treated by hip arthroplasty. The data of 178 elderly patients with femoral neck fracture treated with artificial hip replacement were analyzed. According to whether low molecular weight heparin anticoagulant was used before replacement, patients were divided into anticoagulant group and non-anticoagulant group. The venous thrombosis of the lower extremity was monitored by color ultrasound examination on the 5th day, 5-7 days after the injury and 714 days after the operation. The number and incidence of thrombus were recorded and counted in two groups at different time points. The time points of high incidence of thrombus after injury and after operation were determined by drawing frequency distribution table and broken line graph. Results and conclusion in 72 cases of anticoagulant group, 6 cases of thrombus occurred in 6 cases of anticoagulant group. In the non-anticoagulant group, 22 cases of thrombus occurred in 106 cases and there was a significant difference between the two groups (P 0.05). (2) Thrombosis occurred 3 days after injury and 1 day after operation. Conclusion: the peak time of thrombosis in patients with femoral neck fracture is 1-3 days after injury and 1 day after joint replacement. Preventive measures can significantly reduce the occurrence of venous thrombosis in lower extremity.
【作者单位】：承德医学院附属医院创伤骨科;承德医学院附属医院新生儿科;
【基金】：承德市科技局资助课题(201601A045)~~
【分类号】：R687.4
【正文快照】： 文章快速阅读:文题释义:静脉血栓栓塞症:是骨科大手术后发生率较高的并发症,也是患者围手术期死亡及医院内非预期死亡的重要因素之一。对骨科大手术患者施以有效的抗凝预防措施,不仅可以降低静脉血栓栓塞症的发生率、死亡率,而且可以减轻患者痛苦,降低医疗费用。股骨颈骨折:股

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