腓肠肌外侧头肌瓣联合植皮切口感染炎性因子表达对预后的影响分析

发布时间：2018-02-13 09:34

本文关键词： 胫骨外侧平台骨折腓肠肌外侧头肌瓣植皮切口感染炎性因子　出处：《中华医院感染学杂志》2017年16期 　论文类型：期刊论文

【摘要】：目的探究腓肠肌外侧头肌瓣联合植皮对胫骨外侧平台骨折术后切口感染的预后及炎性因子的水平影响分析。方法选取2014年5月-2016年5月于医院骨科进行手术治疗的胫骨外侧平台骨折且术后出现切口感染患者60例,采用前瞻性随机对照研究,将患者随机分为对照组和观察组,每组各30例;对照组患者给予彻底清创,观察组患者在对照组基础上给予腓肠肌外侧头肌瓣联合植皮治疗,比较两组患者术后切口感染的预后及炎性因子水平。结果观察组患者切口感染治愈率为96.67%,明显高于对照组的80.00%,观察组患者美观率93.33%,明显高于对照组的63.33%,差异有统计学意义(P0.05),两组患者的色泽弹性差异明显(P0.05);治疗前,两组患者Enneking下肢功能评分差异无统计学意义,治疗后,观察组患者评分明显高于对照组,差异有统计学意义(P0.05);观察组患者骨折愈合率为96.67%,对照组为76.67%,差异有统计学意义(P0.05);观察组患者切口愈合时间明显短于对照组,差异有统计学意义(P0.05);治疗后,观察组患者白介素-6(IL-6)、白介素-8(IL-8)、肿瘤坏死因子-α(TNF-α)水平明显低于对照组,差异有统计学意义(P0.05)。结论腓肠肌外侧头肌瓣联合植皮治疗胫骨外侧平台骨折术后切口感染疗效确切,值得临床推广。
[Abstract]:Objective to investigate the effect of gastrocnemius lateral head muscle flap combined with skin graft on postoperative wound infection and inflammatory factors in patients with lateral tibial plateau fracture. Methods from May 2014 to May 2016, surgical treatment was performed in hospital orthopedics department. Of the 60 patients with lateral tibial plateau fracture and postoperative incision infection, The patients were randomly divided into control group (n = 30) and observation group (n = 30). The patients in the control group were treated with complete debridement and the patients in the observation group were treated with gastrocnemius lateral head muscle flap combined with skin grafting on the basis of the control group. Results the cure rate of incision infection in the observation group was 96.67, which was significantly higher than that in the control group. The aesthetic rate of the observation group was 93.33, which was significantly higher than that of the control group. The difference in color and color elasticity between the two groups was significant (P 0.05). There was no significant difference in Enneking scores between the two groups. After treatment, the scores of patients in the observation group were significantly higher than those in the control group. The rate of fracture healing was 96.67 in the observation group and 76.67 in the control group (P 0.05). The healing time of the incision in the observation group was significantly shorter than that in the control group (P 0.05); after treatment, the healing time of the patients in the observation group was significantly shorter than that in the control group (P 0.05). The levels of IL-6, IL-8, TNF- 伪 and TNF- 伪 in the observation group were significantly lower than those in the control group (P 0.05). It is worth popularizing in clinic.
【作者单位】：河南省直第三人民医院骨一科;
【分类号】：R687.3

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