麻醉诱导前应用右美托咪定对老年腹部肿瘤手术患者术后镇痛和镇静效果的影响

发布时间：2018-02-17 07:57

本文关键词： 右美托咪定腹部肿瘤手术镇痛镇静　出处：《中国老年学杂志》2017年16期 　论文类型：期刊论文

【摘要】：目的评估麻醉诱导前应用右美托咪定对老年腹部肿瘤手术患者术后镇痛和镇静效果的影响。方法以行腹部肿瘤手术老年患者120例为研究对象,随机分为观察组(60例)和对照组(60例)。观察组患者在麻醉诱导前给予静脉泵注右美托咪定,对照组患者麻醉诱导前静脉泵注生理盐水。比较两组患者术后3、6、12、24、48 h各时间点的视觉模拟评分(VAS)、Ramsay镇静评分,比较两组患者术后48 h自控镇痛泵的使用次数和不良反应情况。结果观察组术后6、12、24、48 h的VAS评分分别为(4.33±0.91)、(3.06±0.66)、(2.39±0.61)和(2.30±0.60),均明显低于对照组(P0.05)。观察组术后12、24、48 h的Ramsay评分分别为(0.90±0.36)、(0.91±0.39)和(0.86±0.36),均明显低于对照组(P0.05)。观察组术后48 h的自控镇痛泵的使用次数为(1.91±0.81),对照为(5.81±1.33),两组间差异显著(P0.05)。观察组的不良反应发生率明显低于对照组(10.0%vs.26.7%)(P0.05)。结论麻醉诱导前应用右美托咪定能明显改善老年腹部肿瘤手术患者的术后疼痛,起到较好的镇静作用,且不良反应少。
[Abstract]:Objective to evaluate the effect of dexmetomidine before anesthesia induction on postoperative analgesia and sedation in elderly patients with abdominal tumor. Patients in the observation group were given intravenous injection of dexmetomidine before anesthesia induction, and 60 patients in the control group were treated with dexmetidine before anesthesia induction. Patients in the control group were treated with intravenous infusion of normal saline before anesthesia induction. Visual analogue scores and Ramsay sedation scores were compared between the two groups at each time point of 48 hours after operation. Results the VAS scores of the two groups were 4.33 卤0.91 卤0.66 卤0.61 and 2.39 卤0.61 respectively, which were significantly lower than those of the control group (P0.055.The Ramsay scores of the observation group at 12 ~ 2448 h) were significantly lower than those of the control group (P < 0.05). Both 0.90 卤0.36 + 0.91 卤0.39) and 0.86 卤0.36 were significantly lower than those of the control group (P 0.05). The frequency of use of the self-controlled analgesic pump in the observation group at 48 hours after operation was 1.91 卤0.81 卤1.33, and the difference between the two groups was significant (P0.055.The incidence of adverse reactions in the observation group was significantly lower than that in the control group (10.0vs.26.7). Conclusion the incidence of adverse reactions in the observation group was significantly lower than that in the control group (10.0vs.26.7) before induction of anesthesia. Dexmetomidine can significantly improve postoperative pain in elderly patients with abdominal neoplasms. It has a good sedative effect and less adverse reactions.
【作者单位】：自贡市第四人民医院麻醉科;
【分类号】：R614;R730.5

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