呼和浩特地区人群中应用FRAX骨折风险预测工具进行骨折风险评估的临床研究

发布时间：2018-02-20 03:59

本文关键词： 骨质疏松症骨折蒙古族 FRAX 骨折风险评估　出处：《中国骨质疏松杂志》2017年08期 　论文类型：期刊论文

【摘要】：目的探讨FRAX骨折风险预测工具评价呼和浩特蒙古族与汉族人群的骨折风险性的临床应用性。方法选取2016年1月至2016年6月在我院检查者435例(蒙古族56例,汉族379例),收集FRAX风险评估工具所需各项危险因素,输入FRAX中国版,计算10年内主要部位(包括髋部、脊柱、肱骨近端及腕部)及髋部骨折的概率,比较不同民族FRAX预测值。结果354例女性研究对象中,蒙古族女性未来10年主要部位骨折概率1.1%~20.5%,髋部骨折概率0%~13%,汉族女性未来10年主要部位骨折概率1.1%~28.8%,髋部骨折概率0%~27%。81例男性研究对象中,蒙古族男性未来10年主要部位骨折概率1.2%~7.3%,髋部骨折概率0%~4%,汉族男性未来10年主要部位骨折概率1.1%~17.7%,髋部骨折概率0%~6.8%。蒙古族与汉族主要部位骨折及髋部骨折概率之间比较无明显差异(P0.05),然而蒙古族人群股骨颈及腰椎骨密度显著高于汉族人群(P0.05)。结论呼和浩特地区蒙古族人群未来10年髋部骨折与主要部位骨折风险性与汉族人群未表现出明显差异。
[Abstract]:Objective to explore the clinical application of FRAX fracture risk prediction tool to evaluate the fracture risk of Mongolian and Han population in Hohhot. Methods from January 2016 to June 2016, 435 patients (56 Mongols) in our hospital were selected. All the risk factors needed for FRAX risk assessment were collected in 379 cases of Han nationality, and the probability of fracture of hip (including hip, spine, proximal humerus and wrist) and hip fracture was calculated. Results among 354 female subjects, The probability of fracture in the main part of Mongolian women in the next 10 years was 1.1 and 20.5. the probability of fracture of hip was 0.13. The probability of fracture of main part of Han nationality in the next 10 years was 1.1and 28.8. the probability of fracture of hip was 0.27.81 male subjects. The probability of fracture in the main part of Mongolian nationality in the next 10 years is 1.2 / 7.3, the probability of fracture of hip is 0 / 4, the probability of fracture of main part in Han nationality is 1.1and 17.7in the next 10 years, and the probability of fracture of hip is 0.6.8. between Mongolian and Han nationality, the probability of fracture of main part and hip is between Mongolian and Han nationality. However, the bone mineral density of femoral neck and lumbar vertebrae in Mongolian population was significantly higher than that in Han population. Conclusion the hip fracture and main part fracture risk of Mongolian population in Huhehaote area in the next 10 years is not significantly higher than that of Han nationality population. Show obvious difference.
【作者单位】：内蒙古医科大学第二附属医院骨内科;
【基金】：内蒙古自治区高等学校科学研究项目自然科学重点类(NJSY16102) 内蒙古医科大学第二附属医院基金项目(2015YJJS016) 内蒙古自治区已留学人员科技活动项目择优资助项目(2015025)
【分类号】：R580;R683

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