右美托咪啶复合舒芬太尼全身麻醉对剖宫产术中新生儿氧摄取率的影响

发布时间：2018-02-26 04:32

本文关键词： 剖宫产术麻醉全身右美托咪啶舒芬太尼　出处：《中国全科医学》2017年S1期 　论文类型：期刊论文

【摘要】：目的探讨在剖宫产手术过程中运用右美托咪啶复合舒芬太尼全身麻醉的麻醉效果以及对新生儿氧摄取率的影响。方法对2013年11月—2015年11月期间在瑞安市妇幼保健院产科进行剖宫产手术的100例产妇的病历资料进行回顾性分析,将采用右美托咪啶复合舒芬太尼全身麻醉的50例产妇设为观察组,将只进行舒芬太尼麻醉的50例产妇设为对照组。对两组产妇的麻醉效果、注入麻醉剂后不同时间点血清皮质醇水平、新生儿基本情况以及脐血血气进行比较。结果观察组产妇术后的第4 h、第8 h、第24 h的视觉模拟(VAS)评分均低于对照组(P0.05),两组产妇麻醉后1 h血清皮质醇水平高于麻醉前和术后24 h(P0.05),观察组新生儿的麻醉至胎儿娩出的时间(ID)短于对照组(P0.05),观察组1 min新生儿Apgar评分高于对照组(P0.05),两组新生儿的术前胎心、切开子宫至胎儿娩出时间(U-D)、氧代谢指标(ERO_2)、5 min新生儿Apgar评分比较,差异无统计学意义(P0.05),两组新生儿脐动脉血、脐静脉血的p H值、氧分压(PO_2)、血红蛋白(Hb)、二氧化碳分压(PCO_2)比较,差异无统计学意义(P0.05)。结论右美托咪啶复合舒芬太尼联合麻醉可增加新生儿氧摄取率,减少麻醉至胎儿娩出的时间。
[Abstract]:Objective to investigate the anesthetic effect of dexmetomidine combined with sufentanil during cesarean section and its effect on neonatal oxygen uptake. Methods Maternal and Child Health Care in Ruian City from November 2013 to November 2015 was studied. The medical records of 100 pregnant women undergoing cesarean section were retrospectively analyzed. Fifty cases of general anesthesia with dexmetidine combined with sufentanil were set up as observation group and 50 cases of parturient with sufentanil anaesthesia as control group. Serum cortisol levels at different time points after injection of anesthetic, Results the visual analogue VASs in the observation group were lower than those in the control group at 4 h, 8 h and 24 h after anesthesia, and the serum cortisol level in the two groups was higher than that in the control group at 1 h after anesthesia. Before and 24 hours after anesthesia, the time between anesthesia and fetal delivery in the observation group was shorter than that in the control group (P 0.05). The neonatal Apgar score in the observation group 1 min was higher than that in the control group (P 0.05). There was no significant difference in neonatal Apgar scores between the two groups in terms of the time of uterine incision to fetal delivery, the oxygen metabolism index and the neonatal Apgar score of 5 min. There was no significant difference between the two groups in umbilical artery blood, umbilical vein blood pH value, partial pressure of oxygen (PO2P), hemoglobin hbn, carbon dioxide partial pressure PCO2 (PCO2). Conclusion combined anesthesia with dexmetidine and sufentanil can increase oxygen uptake rate and reduce the time between anesthesia and delivery of fetus.
【作者单位】：浙江省瑞安市妇幼保健院;
【分类号】：R614

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