经皮肝胆囊穿刺置管引流术对老年急性胆囊炎患者IL-2、IL-4、IL-6水平与胃肠功能的影响

发布时间：2018-03-01 01:00

本文关键词： 胆囊穿刺置管引流术急性胆囊炎　出处：《中国老年学杂志》2017年05期 　论文类型：期刊论文

【摘要】：目的探讨经皮肝胆囊穿刺置管引流术(PTGCD)对老年急性胆囊炎患者炎症指标与胃肠功能的影响。方法回顾性分析该院收治的52例老年急性胆囊炎患者,根据治疗方法分为PTGCD组和对照组,对照组22例采取胆囊造瘘术进行治疗,PTGCD组30例在超声辅助下行PTGCD术,比较两组患者术前1 d和术后3 d血清白细胞介素(IL)-2、IL-4、IL-6水平,并记录患者术后肛门排气时间、排便时间和进食固体食物的时间。结果 PTGCD组患者均经一次置管成功,术后无明显不良并发症。与术前比较,两组患者术后血清IL-4、IL-6水平均有所上升,但PTGCD组上升的幅度较小。IL-2水平均有所降低(均P0.05)。PTGCD组术后平均肛门排气时间、排便时间和进食固体食物的时间均显著低于对照组(P0.05)。结论 PTGCD治疗结石性胆囊炎疗效安全可靠,可有效降低炎症因子水平,促进肠胃功能恢复。
[Abstract]:Objective to investigate the effect of percutaneous transhepatic cholecystectomy (PTGCD) on inflammatory indexes and gastrointestinal function in elderly patients with acute cholecystitis. Methods 52 elderly patients with acute cholecystitis treated in our hospital were retrospectively analyzed. According to the treatment methods, the PTGCD group and the control group were divided into two groups. The control group (n = 22) received cholecystostomy and 30 patients in the control group (n = 30) were treated with ultrasound assisted PTGCD. The serum levels of IL-2IL-4 and IL-6 were compared between the two groups on the 1st day before operation and 3 days after operation. The time of anal exhaust, defecation and eating solid food were recorded after operation. Results the patients in PTGCD group were successfully placed tube once, and there were no obvious complications after operation. The serum levels of IL-4 and IL-6 increased in both groups, but the amplitude of increase in PTGCD group was smaller. The level of IL-2 was decreased in both groups (P0.05. PTGCD group), and the mean anal exhaust time was lower in the PTGCD group than that in the P0.05. PTGCD group. The time of defecation and the time of eating solid food were significantly lower than that of control group (P0.050.Conclusion PTGCD is safe and reliable in the treatment of calculous cholecystitis, it can effectively reduce the level of inflammatory factors and promote the recovery of gastrointestinal function.
【作者单位】：遵义医学院附属贵航三00医院;
【分类号】：R657.41

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