右美托咪定联合地佐辛在ICU机械通气患者中镇痛镇静的效果

发布时间：2018-03-04 23:08

本文选题：右美托咪定　切入点：芬太尼　出处：《临床麻醉学杂志》2017年08期 　论文类型：期刊论文

【摘要】：目的观察右美托咪定联合地佐辛或芬太尼在ICU机械通气患者术后镇痛镇静的效果。方法选择2016年6~12月我院ICU机械通气患者57例,男35例,女22例,年龄18~75岁,将患者按随机数字表法分为三组:右美托咪定组(A组,n=17例)、右美托咪定联合芬太尼组(B组,n=20例)和右美托咪定联合地佐辛组(C组,n=20例)。比较三组患者一般状况、疼痛评分、用药前后MAP和HR、达理想镇痛镇静的时间、机械通气总时间等指标。结果三组一般资料、重症疼痛观察(CPOT)评分、治疗前后不同时点MAP和HR、机械通气时间差异无统计学意义,达到理想镇静镇痛的时间C组明显快于A组和B组(P0.05)。结论右美托咪定联合地佐辛较单用右美托咪定及右美托咪定联合芬太尼能更快达到理想镇静镇痛效果。
[Abstract]:Objective to observe the analgesic and sedation effect of dexmetomidine combined with dizosin or fentanyl in patients undergoing ICU mechanical ventilation. Methods from 2016 to December, 57 patients (35 males and 22 females, aged 1875 years) with ICU mechanical ventilation in our hospital were selected. The patients were randomly divided into three groups: dexmetomidine group (n = 17), dexmetoimidine plus fentanyl group (n = 20) and dexmetoimidine combined with dizoxin group (n = 20). Results there was no significant difference in the time of mechanical ventilation between the three groups, the general data of the three groups, the score of severe pain observation and the MAP and HRat at different time points before and after treatment, and there was no significant difference in the time of mechanical ventilation between the three groups before and after treatment, and there was no significant difference in the time of mechanical ventilation between the three groups before and after treatment. The time to achieve ideal sedation and analgesia in group C was significantly faster than that in group A and group B. conclusion the effect of dexmetomidine combined with dizosin is faster than that of dexmetomidine and dexmetomidine combined with fentanyl.
【作者单位】：清华大学附属北京清华长庚医院清华大学临床医学院;
【分类号】：R614

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