目标导向液体治疗对腹腔镜卵巢癌根治术患者肝肾功能的影响

发布时间：2018-03-06 17:50

本文选题：目标导向液体治疗　切入点：腹腔镜　出处：《重庆医学》2017年11期 　论文类型：期刊论文

【摘要】：目的探讨目标导向液体治疗对腹腔镜卵巢癌根治术患者肝肾功能的影响。方法选取华北理工大学附属医院2013年2月至2015年2月腹腔镜卵巢癌根治术患者142例,分为观察组和对照组,每组71例。对照组实施传统补液方案,观察组实施目标导向液体治疗。记录两组手术时间、术中出血量、术后排气时间、术后进食时间、术后住院时间、体液容量、术后不良反应,检测手术前后谷氨酸氨基转移酶、天门冬氨酸氨基转移酶、清蛋白、直接胆红素、总胆红素、尿素氮、血肌酐水平。结果两组手术前后谷氨酸氨基转移酶、天门冬氨酸氨基转移酶、清蛋白、直接胆红素、总胆红素、尿素氮、血肌酐比较差异有统计学意义(P0.05)。观察组术后谷氨酸氨基转移酶、天门冬氨酸氨基转移酶、直接胆红素、总胆红素、尿素氮、血肌酐、并发症发生率明显低于对照组(P0.05),清蛋白明显高于对照组(P0.05)。观察组术后排气时间、术后进食时间明显早于对照组(P0.05),术后住院时间、晶体液量、总输入量明显少于对照组(P0.05),尿量、胶体液量明显多于对照组(P0.05)。结论与传统补液方案相比,目标导向液体治疗可减轻腹腔镜卵巢癌根治术对患者肝肾功能的影响,提高安全性。
[Abstract]:Objective to investigate the effect of goal-oriented fluid therapy on liver and kidney function of patients undergoing laparoscopic radical ovarian cancer surgery. Methods 142 patients with laparoscopic radical ovarian cancer were selected from February 2013 to February 2015 in affiliated Hospital of North China University of Technology. The patients were divided into observation group and control group with 71 cases in each group. The control group was given traditional fluid rehydration scheme, the observation group was treated with targeted fluid therapy. The operation time, intraoperative bleeding volume, postoperative exhaust time, postoperative feeding time and postoperative hospitalization time were recorded in the two groups. Body fluid volume, postoperative adverse reactions, detection of glutamate aminotransferase, aspartate aminotransferase, albumin, direct bilirubin, total bilirubin, urea nitrogen before and after operation, Results before and after operation, glutamate aminotransferase, aspartate aminotransferase, albumin, direct bilirubin, total bilirubin, urea nitrogen, The difference of serum creatinine was statistically significant (P 0.05). Glutamate aminotransferase, aspartate aminotransferase, direct bilirubin, total bilirubin, urea nitrogen, serum creatinine were found in the observation group. The incidence of complications was significantly lower than that of the control group (P 0.05), and the level of albumin was significantly higher than that of the control group (P 0.05). The postoperative exhaust time and the postoperative feeding time in the observation group were significantly earlier than those in the control group (P 0.05). The postoperative hospitalization time, the amount of crystal fluid and the total input volume were significantly lower than those in the control group (P 0.05). Conclusion compared with the traditional fluid rehydration regimen, the goal-oriented liquid therapy can reduce the effect of laparoscopic radical operation on liver and kidney function and improve the safety.
【作者单位】：华北理工大学附属医院麻醉科;河北省唐山市妇幼保健院麻醉科;河北省唐山市开平区医院麻醉科;开滦总医院林西医院妇产科;
【基金】：河北省医学科学研究重点课题(20170200) 华北理工大学科学研究基金(Z201602) 河北省高等学校科学技术研究指导项目(Z2015006)
【分类号】：R614;R737.31

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