青少年特发性胸腰弯脊柱侧凸伴结构性腰弯患者腰椎椎体磁共振弥散成像参数的变化

发布时间：2018-03-06 20:18

本文选题：特发性脊柱侧凸　切入点：腰椎　出处：《中国脊柱脊髓杂志》2016年12期 　论文类型：期刊论文

【摘要】：目的 :探讨青少年特发性胸腰弯脊柱侧凸伴结构性腰弯患者腰椎(L1~L5)椎体凹凸侧磁共振弥散加权成像(diffusion-weighted imaging,DWI)参数的变化规律。方法:收集2015年6月~2016年6月在我院就诊的青少年特发性胸腰弯脊柱侧凸伴结构性腰弯的女性患者共30例,年龄10~18岁,Cobb角40°~60°。对患者(侧凸组)及10例同年龄段健康青少年(对照组)腰椎(L1~L5)椎体进行磁共振DWI,测量侧凸患者腰椎椎体凹凸侧及对照组腰椎椎体左右侧表观弥散系数(apparent diffusion coefficient,ADC)值,分别对侧凸患者腰椎椎体凹凸侧及对照组腰椎椎体左右侧ADC值进行比较,同时对侧凸患者和对照组腰椎椎体ADC均值进行比较,分析顶椎椎体凹凸侧ADC差值与Cobb角之间的关系。结果:对照组腰椎各节段间椎体(L1~L5)左侧/右侧的ADC值均无显著性差异(F=0.752,P=0.559;F=0.604,P=0.661);侧凸组腰椎各节段间椎体凹侧/凸侧的ADC值亦无显著性差异性(F=1.268,P=0.301;F=1.250,P=0.291)。对照组腰椎椎体左侧ADC值与右侧比较无显著性差异[(0.439±0.041)×10~(-3)mm~2/s vs(0.423±0.042)×10~(-3)mm~2/s,t=1.047,P=0.288];侧凸组腰椎椎体凹侧ADC值与凸侧比较有显著性差异[(0.391±0.012)×10~(-3)mm~2/s vs(0.553±0.037)×10~(-3)mm~2/s,P0.01],凸侧ADC值与对照组比较显著性增大,凹侧与对照组比较显著性减小。顶椎椎体凹凸侧ADC差值与Cobb角无显著相关性(r=0.024,P=0.721)。结论 :青少年特发性胸腰弯脊柱侧凸伴结构性腰弯患者腰椎(L1~L5)椎体凹凸侧DWI参数存在显著性差异。
[Abstract]:Objective: to investigate the changes of diffusion-weighted diffusion-weighted imaging (DWI) parameters in the concave and convex side of the lumbar vertebrae in adolescent idiopathic thoracolumbar scoliosis with structural lumbar curvature. Methods: from June 2015 to June 2016, we collected the data of diffusion-weighted imaging in our hospital from June 2015 to June 2016. A total of 30 female patients with idiopathic thoracolumbar scoliosis and structural lumbar bending were enrolled. The age of 10 to 18 years old was 40 掳to 60 掳. Magnetic resonance imaging (DWI) was used to measure the left and right side of lumbar vertebrae in patients with scoliosis and 10 healthy adolescents of the same age (control group). The dispersion coefficient is diffusion diffusion coefficient. The ADC values of left and right sides of lumbar vertebrae in patients with scoliosis and those in control group were compared, and the mean ADC of lumbar vertebrae in patients with scoliosis and control group were compared. Results: there was no significant difference in ADC value between left and right side of lumbar vertebrae in the control group. ADC was 0.604 / 0.661in the lumbar intervertebral concave side / convex side of the lumbar vertebrae in the kyphosis group, and ADC in the concave / convex side of the lumbar vertebrae between the different segments of the lumbar vertebrae in the kyphosis group was not significantly different from that of the control group in the left and right side of the lumbar vertebrae (P < 0. 752 / P = 0. 555 9 / P = 0. 604 / 0. 661). There was no significant difference in the value of left side ADC between the control group and the right side [0. 439 卤0. 041) 脳 10 ~ (-3) vs(0.423 卤0. 042) 脳 10 ~ (-3) 卤0. 042) 脳 10 ~ (-3) mm ~ (-1) ADC = 1. 047 ~ 0. 288; there was a significant difference in ADC value between the concave side of the kyphosis group and the protruding side [0. 391 卤0. 012) 脳 10 ~ (-3) mm vs(0.553 卤0. 037 脳 10 ~ (-1) 卤0. 037 脳 10 ~ (-3) mm ~ (2mm) P _ (1). The ADC value of the kyphosis group was significantly larger than that of the control group (P < 0. 88), and the ADC value of the kyphosis group was significantly larger than that of the control group (P < 0. 001 卤0. 012), and the ADC value of the kyphosis group was significantly larger than that of the control group. There was no significant correlation between the ADC difference of concave and convex side and Cobb angle. Conclusion: the DWI parameter of L1L5 in adolescent idiopathic thoracolumbar scoliosis with structural lumbar curvature is not significantly correlated with Cobb angle. There was significant difference.
【作者单位】：南京中医药大学中西医结合鼓楼临床医学院;
【基金】：国家自然科学基金资助项目(编号:81371516)
【分类号】：R726.8

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