骨骼肌卫星细胞成肌化机制研究进展

发布时间：2018-03-21 00:23

本文选题：卫星细胞　切入点：骨骼肌　出处：《医学研究生学报》2016年09期 　论文类型：期刊论文

【摘要】：骨骼肌是人体的重要组织,除运动、呼吸、循环系统等方面的作用外,骨骼肌还是一个分泌组织并参与信号传导。随着卫星细胞的发现及其成肌化机制研究的深入,颠覆了骨骼肌损伤是不可逆的观点。卫星细胞可通过增殖活化、分化、融合成肌纤维修复骨骼肌损伤,其成肌化受多种因素的影响。文中将从调控因子、细胞外基质、衰老、表观遗传因子、疾病等影响因素的研究进展进行综述。
[Abstract]:Skeletal muscle is an important tissue of human body. In addition to the functions of movement, respiration and circulatory system, skeletal muscle is also a secretory tissue and participates in signal transduction. It overturns the view that skeletal muscle injury is irreversible. Satellite cells can repair skeletal muscle damage through proliferation, activation, differentiation, fusion of muscle fibers, and its myogenesis is affected by many factors. The research progress of epigenetic factors, diseases and other influencing factors are reviewed.
【作者单位】：昆明医科大学第二附属医院泌尿外科;
【基金】：云南省科技计划项目(2015FA007)
【分类号】：R68

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