关节镜下广泛清理术联合术后得宝松、血栓通关节腔注射治疗膝关节痛风性关节炎16例

发布时间：2018-03-24 18:43

本文选题：膝关节炎　切入点：痛风性关节炎　出处：《山东医药》2017年39期

【摘要】：目的观察关节镜下广泛清理术联合术后得宝松、血栓通关节腔注射治疗膝关节痛风性关节炎的临床疗效。方法膝关节痛风性关节炎患者31例,采用关节镜下广泛清理术治疗。术后第2天关节腔内注射得宝松1m L、血栓通150 mg,每周1次,共3次。观察术前及术后1年膝关节活动度(ROM),进行视觉模拟评分(VAS)、膝关节Lysholm评分和WOMAC骨性关节炎指数评分,检测血尿酸(BUA)、红细胞沉降率(ESR)及C反应蛋白(CRP)。记录治疗过程中出现的不良反应,GA复发情况。结果所有患者均获得随访,随访12~89个月。与术前相比,术后1年患者膝关节ROM明显增大,VAS评分、WOMAC评分降低,膝关节Lysholm评分提高,血BUA、ESR及CRP水平显著下降(P均0.05)。所有患者在随访过程中均未出现切口及关节内感染、重要神经损伤及下肢静脉血栓形成等严重并发症。结论关节镜下广泛清理术联合术后得宝松、血栓通关节腔注射治疗膝关节痛风性关节炎可改善膝关节功能,缓解疼痛,控制炎症反应,延缓病程进展。
[Abstract]:Objective to observe the clinical effect of extensive debridement under arthroscopy combined with intraarticular injection of Teproxone and thrombus in the treatment of gouty arthritis of knee joint. Methods 31 cases of knee joint gouty arthritis were treated. After the second day of operation, intraarticular injection of Diproxone 1m L, Xueshuantong 150 mg, once a week, 2 days after operation, the patients were treated with extensive debridement under arthroscopy. The knee motion was observed before and 1 year after operation. Visual analogue score (VAS), knee joint Lysholm score (Lysholm) and WOMAC osteoarthritis index (WOMAC) were evaluated. Blood uric acid BUAA, erythrocyte sedimentation rate (ESRR) and C-reactive protein (C-reactive protein) were detected. The recurrence of GA was recorded during the treatment. Results all the patients were followed up for 12 ~ 89 months. One year after operation, the ROM of the knee joint increased significantly and the score of WOMAC decreased, the score of Lysholm of the knee increased, and the levels of CRP and BUASR decreased significantly (P < 0.05). No incision or intraarticular infection was found in all the patients during the follow-up. Conclusion extensive debridement under arthroscopy combined with debosone, thrombotic injection into articular cavity for the treatment of gouty arthritis of the knee joint can improve the function of the knee joint and relieve the pain. Control the inflammatory reaction and delay the progress of the disease.
【作者单位】：山东中医药大学;济南市中医医院;山东省千佛山医院;
【分类号】：R687.4

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