瑞芬太尼在中老年患者无痛支气管镜检查中的临床作用

发布时间：2018-03-27 14:50

本文选题：芬太尼　切入点：麻醉　出处：《重庆医学》2017年26期

【摘要】：目的探讨瑞芬太尼在中老年患者无痛支气管镜检查中的作用。方法将120例行无痛支气管镜检查的中老年患者随机分为4组(n=30),A组用丙泊酚麻醉,B、C、D组用瑞芬太尼复合丙泊酚麻醉(瑞芬太尼输注剂量:B组0.05μg·kg~(-1)·min~(-1),C组0.10μg·kg~(-1)·min~(-1),D组0.15μg·kg~(-1)·min~(-1))。观察各组患者在检查过程中的体动反应、血流动力学变化、丙泊酚用量、检查时间、苏醒时间、离室时间及不良反应。结果在检查过程中,A组的术中体动和呛咳明显高于其他3组(P0.05);在血流动力学上,A组波动较大,B、C、D组相对较平稳,但D组低血压、心动过缓、一过性呼吸抑制发生率均较其他3组高(P0.05);丙泊酚用量A组明显高于其他3组(P0.05),B组高于C、D组(P0.05);在苏醒时间和离室时间上B、C、D组明显优于A组(P0.05),C、D组短于B组(P0.05)。结论中老年患者在无痛支气管镜检查中可使用瑞芬太尼,且以0.10μg·kg~(-1)·min~(-1)的瑞芬太尼复合异丙酚麻醉效果较好。
[Abstract]:Objective to investigate the role of remifentanil in painless bronchoscopy in middle-aged and elderly patients. Methods 120 middle-aged and elderly patients with painless bronchoscopy were randomly divided into 4 groups: group A was treated with propofol anesthesia and group D was treated with remifentanil combined with remifentanil. Propofol anesthesia (remifentanil 0.05 渭 g kg 路kg ~ (-1)) in group C (0.10 渭 g 路kg ~ (-1)) 路min ~ (-1) 路min ~ (-1) 路min ~ (-1) 路min ~ (-1) 路min ~ (-1) 路min ~ (-1) 路min ~ (-1) 路min ~ (-1) 路min ~ (-1) 路min ~ (-1) 路min ~ (-1). Hemodynamic changes, propofol dosage, examination time, recovery time, Results the intraoperative body movement and choking cough in group A were significantly higher than those in other three groups (P 0.05), but the hemodynamics of group A was relatively stable, but that of group D was hypotension and bradycardia. The incidence of transient respiratory inhibition was significantly higher in group A than in other three groups, and the dosage of propofol in group A was significantly higher than that in group C (P 0.05), and in group B was higher than that in group C (P 0.05), and in the recovery time and time of absence from room, group B was significantly better than group A (P 0.05) than group B (P 0.05). Conclusion the dosage of propofol in group A is significantly higher than that in group B. Remifentanil may be used in painless bronchoscopy. The anesthetic effect of remifentanil combined with propofol was better than that of remifentanil (0.10 渭 g 路kg ~ (-1)) 路min ~ (-1) 路min ~ (-1).
【作者单位】：解放军第101医院麻醉科;
【分类号】：R614

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