60岁以上瓣膜病患者瓣膜置换术后早期死亡因素的分析

发布时间：2018-04-01 12:23

  本文选题：心脏瓣膜病　切入点：瓣膜置换　出处：《新疆医科大学》2017年硕士论文

【摘要】：目的:探讨60岁以上瓣膜病患者瓣膜置换术后早期死亡的危险因素。方法:回顾性分析2012年4月至2016年4月新疆医科大学第一附属医院收治178例年龄大于60岁老年瓣膜病患者行心脏瓣膜置换术的临床资料,其中男102例,女76例;年龄60~74岁,术前经体格检查,实验室检查及其他综合评定后确诊,均经手术证实,均在全麻体外循环(cardiopulmonary bypass,CPB)下行心脏瓣膜置换术。结果:178例患者中术后发生严重并发症17例(9.5%),死亡10例(5.61%)。临床通过统计学单因素分析可知,CPB时间≥120min、主动脉阻断时间≥60min、有并发症、EF50%、LVEDD≥70mm和同期行CABG术死亡的概率更高,多因素Logistic回归分析显示,体外循环时间≥120min,EF50%;老年心脏瓣膜患者同期行CABG术及有并发症是早期死亡的独立预测因素。结论:根据老年心脏瓣膜病患者的临床特点进行术前评估,针对性的给予老年心脏瓣膜病患者瓣膜置换术治疗有助于延长患者的生存时间,提高患者的生存率,改善患者的预后。
[Abstract]:Objective: to investigate the risk factors of early death after valve replacement in patients over 60 years old. Methods: a retrospective analysis of 178 patients aged over 60 years in the first affiliated Hospital of Xinjiang Medical University from April 2012 to April 2016 was conducted. Clinical data of valve replacement in patients with valvular disease, 102 males and 76 females, aged 60 to 74 years, were diagnosed by physical examination, laboratory examination and other comprehensive assessment before operation, all of which were confirmed by operation. All patients underwent cardiac valve replacement under cardiopulmonary bypass (CPB) under general anesthesia. Results among 178 patients, 17 had severe complications (9.5%) and 10 died (5.61%). Clinical univariate analysis showed that CPB time 鈮，

本文编号：1695575