中频脉冲疗法辅助治疗骨质疏松性桡骨远端骨折的临床效果及机制

发布时间：2018-04-01 18:36

本文选题：桡骨远端骨折　切入点：骨质疏松　出处：《山东医药》2017年16期

【摘要】：目的探讨中频脉冲疗法辅助治疗骨质疏松性桡骨远端骨折的临床效果及其可能的作用机制。方法将90例骨质疏松性桡骨远端骨折患者随机分为观察组及对照组,每组45例。对照组手法牵引复位、石膏固定后给予消炎、止痛、抗骨质疏松等常规治疗,观察组在此基础上给予中频脉冲治疗,30 min/次,2次/d;两组疗程均为45天。两组治疗后行腕关节正侧位X线检查,记录骨痂量化评分;采用ELISA法检测治疗前后血清骨硬化蛋白(SO)水平;记录两组治疗期间不良反应发生情况。结果观察组治疗后骨痂量化评分为(3.52±0.33)分,对照组为(2.21±0.41)分,两组比较P0.05。观察组治疗前后血清SO水平分别为(375.13±79.80)、(259.10±48.95)pg/m L,对照组分别为(377.20±84.08)、(308.56±58.74)pg/m L;与治疗前比较,两组治疗后血清SO水平均降低,但观察组降低更明显(P均0.05)。两组治疗期间均无皮肤红肿、感觉减退、局部疼痛等不良反应发生。结论中频脉冲疗法辅助治疗可促进骨质疏松性桡骨远端骨折愈合,其机制可能与降低血清SO水平有关。
[Abstract]:Objective to investigate the clinical effect and possible mechanism of intermediate frequency pulse therapy in the treatment of osteoporotic distal radius fractures. Methods 90 patients with osteoporotic distal radius fractures were randomly divided into observation group and control group. Each group of 45 cases. Control group manual traction reduction, plaster fixation after anti-inflammatory, pain relief, anti-osteoporosis and other routine treatment, On this basis, the observation group was treated with intermediate frequency pulse therapy for 30 min/ twice a day, and the course of treatment in both groups was 45 days. After the treatment, the carpal joint X-ray examination was performed and the callus quantitative score was recorded. The level of serum osteosclerotic protein (so) was measured by ELISA method before and after treatment, and the occurrence of adverse reactions in the two groups was recorded. Results the quantitative score of callus after treatment was 3.52 卤0.33 in the observation group and 2.21 卤0.41 in the control group. Before and after treatment, the serum so levels in the observation group and the control group were 375.13 卤79.80 卤259.10 卤48.95)pg/m / L and 308.56 卤58.74)pg/m / L, respectively, compared with those before and after treatment, but the decrease was more significant in the observation group (P < 0.05). Conclusion Intermediate frequency pulse therapy can promote the healing of osteoporotic distal radius fractures, and its mechanism may be related to the reduction of serum so level.
【作者单位】：遵义医学院第五附属医院;
【基金】：贵州省科学技术基金资助项目(黔科合J字LKZ[2013]43号)
【分类号】：R683;R580

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