颈椎间盘退变与吸烟的关系研究

发布时间：2018-04-04 04:43

  本文选题：椎间盘退行性变　切入点：颈椎病　出处：《中国全科医学》2017年34期

【摘要】：目的探讨颈椎间盘退变与吸烟的关系。方法选取2014年6月—2016年6月同济大学附属东方医院脊柱外科门诊因颈肩部疼痛就诊的患者320例,根据烟草燃烧物暴露方式分为非吸烟组(n=141)、被动吸烟组(n=55)、吸烟组(n=124)。纳入患者均接受MRI检查,采用Miyazaki分级评价患者颈椎间盘退变程度,采用视觉模拟评分量表(VAS)评价患者颈肩痛程度。根据3组患者Miyazaki分级和VAS评分探讨颈椎间盘退变与吸烟的关系。结果非吸烟组患者C2/3、C3/4、C5/6节段及总体Miyazaki分级优于被动吸烟组,非吸烟组患者C1/2~C6/7节段及总体Miyazaki分级优于吸烟组,差异有统计学意义(P0.05)。被动吸烟组、吸烟组中,C4/5~C6/7节段Miyazaki分级为Ⅳ、Ⅴ级的椎间盘比例高于C1/2~C3/4节段,差异有统计学意义(P0.05)。吸烟组中,男性Miyazaki分级为Ⅳ、Ⅴ级的椎间盘比例高于女性,差异有统计学意义(P0.05)。被动吸烟组、吸烟组中,吸烟5~10年者Miyazaki分级优于吸烟10年者,差异有统计学意义(P0.05)。3组患者VAS评分有差异,其中吸烟组患者VAS评分高于非吸烟组,差异有统计学意义(P0.05)。结论烟草燃烧物可加速颈椎间盘退变进程,同时患者伴随的颈肩痛程度也有所增加;在影响椎间盘退变的程度上,下颈椎间盘较上颈椎间盘明显。
[Abstract]:Objective to investigate the relationship between cervical disc degeneration and smoking.Methods 320 patients with neck and shoulder pain were selected from the Department of Spinal surgery, Dongfang Hospital affiliated to Tongji University from June 2014 to June 2016. The patients were divided into non-smoking group (n = 141), passive smoking group (n = 55) and smoking group (n = 124).All the patients were examined by MRI, the degree of cervical disc degeneration was evaluated by Miyazaki grade, and the degree of neck and shoulder pain was evaluated by visual analogue scale (VAS).The relationship between cervical disc degeneration and smoking was studied according to Miyazaki grade and VAS score.Results the C _ 2 / 3 / C _ 3 / C _ 3 / 4 C _ 5 / 6 segment and total Miyazaki grade in non-smoking group were better than those in passive smoking group. The C1/2~C6/7 segment and total Miyazaki grade in non-smoking group were better than that in smoking group (P < 0.05).In the passive smoking group, the proportion of intervertebral disc in C4 / 5 / C6 / 7 segment with Miyazaki grade 鈪，

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