抗生素骨水泥间隔体在全膝关节置换术后感染二期翻修中的应用

发布时间：2018-04-10 16:00

本文选题：膝关节置换 + 感染　；参考：《中华医院感染学杂志》2017年09期

【摘要】：目的探讨抗生素骨水泥间隔体在人工膝关节表面置换术(TKA)术后感染二期翻修中的临床疗效。方法对2009年6月-2016年6月在医院骨科接受了TKA术后感染二期翻修的30例患者进行回顾性分析;30例(30膝)患者取出假体,彻底清创,用抗生素骨水泥的功能性假体植入,间隔期膝关节正常活动,待12周感染控制后再行膝关节翻修手术;记录和比较治疗前、间隔期、二期翻修术后的美国膝关节协会(KSS)膝关节评分、KSS膝关节功能评分、KSS膝关节疼痛评分、膝关节活动范围(ROM)值。结果 30例患者均治愈,间隔期末次随访患膝平均屈曲90°,平均美国膝关节协会评分(KSS,81.1±6.7)分,翻修术后患膝平均屈曲95°,KSS(86.3±7.4)分,平均随访时间为37.6个月(31~71)个月,无感染复发。结论采用抗生素骨水泥功能性假体治疗TKA术后感染,临床效果好,膝关节功能恢复良好,可以显著提高患者的长期预后和生活质量。
[Abstract]:Objective to investigate the clinical effect of antibiotic bone cement septum in the second stage revision of infection after artificial knee joint surface replacement (TKA).Methods from June 2009 to June 2016, 30 patients who received the second stage revision of infection after TKA operation in hospital orthopedic department were analyzed retrospectively. The prosthesis was removed from 30 patients, debrided thoroughly and implanted with antibiotic bone cement.Normal activity of knee joint in interval period, after infection control for 12 weeks, revision operation of knee joint was performed again, recording and comparing before and after treatment,The American knee Association (AKS) knee Joint score (KSS) and KSS knee function score (KSS) were used to evaluate the knee pain and the range of knee motion (ROM).Conclusion the use of antibiotic bone cement functional prosthesis in the treatment of postoperative TKA infection has good clinical effect and good recovery of knee joint function. It can significantly improve the long-term prognosis and quality of life of the patients.
【作者单位】：浙江大学医学院附属浙江省第一人民医院骨科;武警浙江省总队医院关节外科;
【基金】：浙江省自然科学基金资助项目(LY14H060002)
【分类号】：R687.4

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