胃肠手术后严重感染和感染性休克的集束化治疗研究

发布时间：2018-04-13 04:11

  本文选题：胃肠手术 + 严重感染　； 参考：《中华医院感染学杂志》2017年24期

【摘要】：目的探讨应用集束化治疗胃肠手术后严重感染和感染性休克患者的临床疗效。方法选择2013年1月-2016年1月于医院就诊的胃肠手术后严重感染合并感染性休克患者共78例,将患者分为试验组40例与对照组38例,试验组采用集束化治疗,对照组采用传统经验性治疗。比较两组患者的临床疗效。结果治疗24h后,试验组患者的乳酸水平、动脉血氧饱和度(SaO2)、每h平均尿量、平均中心静脉压均优于对照组(P0.05);治疗3d后,试验组患者急性生理学及慢性健康状况评分系统Ⅱ(APACHEⅡ)及序贯性器官衰竭评分(SOFA)均低于治疗前及对照组治疗后(P0.05);连续治疗1个月后,试验组患者治疗有效率为92.5%,高于对照组的76.3%(P0.05)。结论应用集束化治疗胃肠手术后严重感染合并感染性休克患者,可降低患者乳酸水平、动脉血氧饱和度及排尿量,降低患者死亡率,是一种较为安全有效的治疗方法。
[Abstract]:Objective to investigate the clinical effect of cluster therapy in patients with severe infection and septic shock after gastrointestinal surgery.Methods from January 2013 to January 2016, 78 patients with severe infection and septic shock after gastrointestinal operation were divided into experimental group (n = 40) and control group (n = 38).The control group was treated with traditional experience therapy.To compare the clinical effect of the two groups.Results after 24 hours of treatment, the levels of lactic acid, arterial oxygen saturation and SAO _ 2, mean urine volume and mean central venous pressure in the test group were higher than those in the control group (P 0.05), and 3 days after treatment, there was no significant difference between the two groups.The acute physiology and chronic health status scoring system 鈪，

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