牛膝醇溶液透药联合硫酸氨基葡萄糖治疗膝骨关节炎的临床观察

发布时间：2018-04-17 22:11

本文选题：牛膝醇溶液 + 透入疗法　；参考：《中国中医骨伤科杂志》2016年12期

【摘要】：目的:观察牛膝醇溶液透药联合硫酸氨基葡萄糖治疗膝骨关节炎的疗效。方法:将75例膝骨关节炎患者采用随机数字表法随机分为3组,每组25例。A组为治疗组,接受牛膝醇溶液透药及口服硫酸氨基葡萄糖治疗,B,C组为对照组,B组只接受牛膝醇溶液透药治疗,C组只口服硫酸氨基葡萄糖治疗,连续治疗6周,透药为每5d后休息2d.观察、比较3组治疗前后视觉模拟系统(VAS)评分、西安大略和麦克马斯特大学骨关节炎指数(WOMAC评分)及膝关节肿胀评分。结果:治疗后3组各项临床评分较治疗前均显著好转(P0.05);其中3组间的VAS评分差异无统计学意义(P0.05),而在WOMAC评分、膝关节肿胀评分上A组优于B,C组,且差异有统计学意义(P0.05),B组和C组间差异无统计学意义(P0.05)。结论:牛膝醇溶液透药联合口服硫酸氨基葡萄糖,较单用牛膝醇溶液和硫酸氨基葡萄糖,对膝骨关节炎疗效更佳,值得临床推广。
[Abstract]:Objective: to observe the therapeutic effect of Achyranthes bidentata solution combined with glucosamine sulfate in the treatment of knee osteoarthritis.Methods: 75 cases of knee osteoarthritis were randomly divided into 3 groups, 25 cases in each group.The rats in group B received only oral glucosamine sulfate for 6 weeks, and the drug permeation group B was treated with glucosamine sulfate only for 6 weeks. The dialystics were given every 5 days and rest for 2 days.The visual analogue system (VAS) score, Osteoarthritis Index (WOMAC) and knee swelling score were compared between the three groups before and after treatment.Results: after treatment, the clinical scores of the three groups improved significantly compared with those before treatment, and the difference of VAS scores among the three groups was not statistically significant (P 0.05). However, in the WOMAC score, the knee swelling score in group A was better than that in group B (C).There was no significant difference between group B and group C (P 0.05).Conclusion: the therapeutic effect of Achyranthol solution combined with oral glucosamine sulfate on knee osteoarthritis is better than that of only Achyranthol solution and glucosamine sulfate. It is worth popularizing in clinic.
【作者单位】：广州中医药大学第四临床医学院;深圳市中医院;
【分类号】：R684.3

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